BDH2

Dehydrogenase that mediates the formation of 2,5-dihydroxybenzoic acid (2,5-DHBA), a siderophore that shares structural similarities with bacterial enterobactin and associates with LCN2, thereby playing a key role in iron homeostasis and transport. Also acts as a 3-hydroxybutyrate dehydrogenase (By similarity).
Full Name
3-Hydroxybutyrate Dehydrogenase 2
Function
Dehydrogenase that mediates the formation of 2,5-dihydroxybenzoic acid (2,5-DHBA), a siderophore that shares structural similarities with bacterial enterobactin and associates with LCN2, thereby playing a key role in iron assimilation and homeostasis. Plays a role in susceptibility to bacterial infection by providing an assimilable source of iron that is exploited by pathogenic bacteria (By similarity).
Also acts as a 3-hydroxybutyrate dehydrogenase (PubMed:16380372).
Biological Process
Epithelial cell differentiation Source: UniProtKB
Fatty acid beta-oxidation Source: HGNC-UCL
Heme metabolic process Source: UniProtKB
Iron ion homeostasis Source: UniProtKB
Ketone body biosynthetic process Source: Reactome
Siderophore biosynthetic process Source: UniProtKB
Cellular Location
Cytoplasm
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Anti-BDH2 antibodies

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Mouse Anti-BDH2 Recombinant Antibody (CBYY-2106) (CBMAB-2455-YY)

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Target: BDH2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Rat
Clone: CBYY-2106
Application*: FC, IF, IH, WB
Datasheet SDS

Mouse Anti-BDH2 Recombinant Antibody (CBYY-2059) (CBMAB-2408-YY)

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Target: BDH2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Rat
Clone: CBYY-2059
Application*: FC, IF, IH, WB
Datasheet SDS

Mouse Anti-BDH2 Recombinant Antibody (CBYY-1999) (CBMAB-2348-YY)

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Target: BDH2
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBYY-1999
Application*: WB, IH, IF, IP
Datasheet SDS

Mouse Anti-BDH2 Recombinant Antibody (CBYY-0464) (CBMAB-0467-YY)

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Target: BDH2
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human, Mouse, Rat, Horse, Dog
Clone: CBYY-0464
Application*: WB, IH, IF, IP
Datasheet SDS

Mouse Anti-BDH2 Recombinant Antibody (CBYY-0462) (CBMAB-0465-YY)

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Target: BDH2
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human, Mouse, Rat
Clone: CBYY-0462
Application*: WB, IH, IF, IP
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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