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Mouse Anti-BDH2 Recombinant Antibody (CBYY-2059) (CBMAB-2408-YY)

This product is mouse antibody that recognizes BDH2. The antibody CBYY-2059 can be used for immunoassay techniques such as: FC, IF, IHC-P, WB
See all BDH2 antibodies

Summary

Host Animal
Mouse
Specificity
Human, Mouse, Rat
Clone
CBYY-2059
Antibody Isotype
IgG1
Application
FC, IF, IHC, WB

Basic Information

Immunogen
Full length human recombinant protein of human BDH2 produced in HEK293T cell.
Host Species
Mouse
Specificity
Human, Mouse, Rat
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.
ApplicationNote
WB1:2,000
IHC1:50
IF(ICC)1:100
FC1:100

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.3, 1% BSA, 50% glycerol
Preservative
0.02% sodium azide
Concentration
Batch dependent
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
3-Hydroxybutyrate Dehydrogenase 2
Introduction
Dehydrogenase that mediates the formation of 2,5-dihydroxybenzoic acid (2,5-DHBA), a siderophore that shares structural similarities with bacterial enterobactin and associates with LCN2, thereby playing a key role in iron homeostasis and transport. Also acts as a 3-hydroxybutyrate dehydrogenase (By similarity).
Entrez Gene ID
UniProt ID
Alternative Names
3-Hydroxybutyrate Dehydrogenase 2; Short Chain Dehydrogenase/Reductase Family 15C Member 1; Dehydrogenase/Reductase SDR Family Member 6; 3-Hydroxybutyrate Dehydrogenase, Type 2; R-Beta-Hydroxybutyrate Dehydrogenase; Oxidoreductase UCPA; SDR15C1; DHRS6; Short Chain Dehydrogenase/Reductase Family 15C, Member 1;
Function
Dehydrogenase that mediates the formation of 2,5-dihydroxybenzoic acid (2,5-DHBA), a siderophore that shares structural similarities with bacterial enterobactin and associates with LCN2, thereby playing a key role in iron assimilation and homeostasis. Plays a role in susceptibility to bacterial infection by providing an assimilable source of iron that is exploited by pathogenic bacteria (By similarity).
Also acts as a 3-hydroxybutyrate dehydrogenase (PubMed:16380372).
Biological Process
Epithelial cell differentiation Source: UniProtKB
Fatty acid beta-oxidation Source: HGNC-UCL
Heme metabolic process Source: UniProtKB
Iron ion homeostasis Source: UniProtKB
Ketone body biosynthetic process Source: Reactome
Siderophore biosynthetic process Source: UniProtKB
Cellular Location
Cytoplasm
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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