CCL25
CCL25 (C-C Motif Chemokine Ligand 25) is a Protein Coding gene. Among its related pathways are PEDF Induced Signaling and Akt Signaling. Gene Ontology (GO) annotations related to this gene include hormone activity and chemokine receptor binding.
Full Name
C-C Motif Chemokine Ligand 25
Function
Potentially involved in T-cell development. Recombinant protein shows chemotactic activity on thymocytes, macrophages, THP-1 cells, and dendritics cells but is inactive on peripheral blood lymphocytes and neutrophils. Binds to CCR9. Isoform 2 is an antagonist of isoform 1. Binds to atypical chemokine receptor ACKR4.
Biological Process
Antimicrobial humoral immune response mediated by antimicrobial peptide Source: UniProtKB
Cell chemotaxis Source: UniProtKB
Cell surface receptor signaling pathway Source: ProtInc
Cellular response to interferon-gamma Source: GO_Central
Cellular response to interleukin-1 Source: GO_Central
Cellular response to tumor necrosis factor Source: GO_Central
Chemokine-mediated signaling pathway Source: GO_Central
Chemotaxis Source: ProtInc
G protein-coupled receptor signaling pathway Source: UniProtKB
Immune response Source: ProtInc
Inflammatory response Source: GO_Central
Killing of cells of other organism Source: UniProtKB
Lymphocyte chemotaxis Source: GO_Central
Monocyte chemotaxis Source: GO_Central
Negative regulation of leukocyte tethering or rolling Source: UniProtKB
Neutrophil chemotaxis Source: GO_Central
Positive regulation of cell-matrix adhesion Source: UniProtKB
Positive regulation of ERK1 and ERK2 cascade Source: GO_Central
Positive regulation of GTPase activity Source: GO_Central
Cell chemotaxis Source: UniProtKB
Cell surface receptor signaling pathway Source: ProtInc
Cellular response to interferon-gamma Source: GO_Central
Cellular response to interleukin-1 Source: GO_Central
Cellular response to tumor necrosis factor Source: GO_Central
Chemokine-mediated signaling pathway Source: GO_Central
Chemotaxis Source: ProtInc
G protein-coupled receptor signaling pathway Source: UniProtKB
Immune response Source: ProtInc
Inflammatory response Source: GO_Central
Killing of cells of other organism Source: UniProtKB
Lymphocyte chemotaxis Source: GO_Central
Monocyte chemotaxis Source: GO_Central
Negative regulation of leukocyte tethering or rolling Source: UniProtKB
Neutrophil chemotaxis Source: GO_Central
Positive regulation of cell-matrix adhesion Source: UniProtKB
Positive regulation of ERK1 and ERK2 cascade Source: GO_Central
Positive regulation of GTPase activity Source: GO_Central
Cellular Location
Secreted
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Anti-CCL25 antibodies
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CompareTarget: CCL25
Host: Rat
Antibody Isotype: IgG2
Specificity: Mouse
Clone: CBYY-C0694
Application*: WB, IH, N
Target: CCL25
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: 89827
Application*: WB, IH, E
Target: CCL25
Host: Rat
Antibody Isotype: IgG2b
Specificity: Mouse
Clone: 89818
Application*: WB, N
Target: CCL25
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 52513
Application*: E, WB
Target: CCL25
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBXC-1233
Application*: E, WB
Target: CCL25
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBXC-1232
Application*: E, N, WB
Target: CCL25
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBYJT-1062
Application*: E, I, WB
Target: CCL25
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYC-0971
Application*: E
Target: CCL25
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: CBFYC-0970
Application*: P, IF, WB, E, IP
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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