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CCR9

CCR9 (C-C Motif Chemokine Receptor 9) is a Protein Coding gene. Diseases associated with CCR9 include Celiac Disease 1 and Cd45 Deficiency. Among its related pathways are Akt Signaling and Allograft rejection. Gene Ontology (GO) annotations related to this gene include G-protein coupled receptor activity and C-C chemokine receptor activity. An important paralog of this gene is CCR7.

Full Name

C-C Motif Chemokine Receptor 9

Function

Receptor for chemokine SCYA25/TECK. Subsequently transduces a signal by increasing the intracellular calcium ions level.
(Microbial infection) Alternative coreceptor with CD4 for HIV-1 infection.

Biological Process

Calcium-mediated signaling Source: GO_Central
CD8-positive, gamma-delta intraepithelial T cell differentiation Source: Ensembl
Cell chemotaxis Source: GO_Central
Cellular defense response Source: ProtInc
Chemotaxis Source: ProtInc
G protein-coupled receptor signaling pathway Source: Reactome
Immune response Source: GO_Central
Positive regulation of cytosolic calcium ion concentration Source: GO_Central
Viral process Source: UniProtKB-KW

Cellular Location

Cell membrane

Topology

Extracellular: 1-48
Helical: 49-74
Cytoplasmic: 75-85
Helical: 86-109
Extracellular: 110-120
Helical: 121-150
Cytoplasmic: 151-159
Helical: 160-185
Extracellular: 186-208
Helical: 209-243
Cytoplasmic: 244-248
Helical: 249-283
Extracellular: 284-290
Helical: 291-321
Cytoplasmic: 322-369

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Anti-CCR9 antibodies

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Mouse Anti-CCR9 Recombinant Antibody (6D10) (CBMAB-C8145-LY)

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Target: CCR9

Host: Mouse

Antibody Isotype: IgG2

Specificity: Human

Clone: 6D10

Application*: F, IH

Human CCR9 ELISA Kit (V2LY-0626-LY4370)

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Target: CCR9

Sensitivity: 0.0074 ng/mL

Detection Range: 0.015-3 ng/mL

Sample Type: Serum, Plasma, cell culture supernates

Specificity: Human

Assay Type: Sandwich

Reactivity: Human

Human Recombinant CCR9-VLP protein, Flag & His-Strep Tag (V2LY-0526-LY2650)

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Target: CCR9

Expressed Host: HEK293 Cells

Sequence: Amino Acid: 1-369

Tag: Flag & His-Strep Tag

Human Anti-CCR9 Recombinant Antibody (
8H4) (V2LY-0725-LY628)

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Target: CCR9

Host: Human

Antibody Isotype: IgG1

Specificity: Human

Clone: 8H4

Application*: E

Rabbit Anti-CCR9 Recombinant Antibody (
4G2) (V2LY-0725-LY627)

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Target: CCR9

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human

Clone: 4G2

Application*: E, IF

Rabbit Anti-CCR9 Recombinant Antibody (CBNH-016) (CBMAB-R4341-CN)

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Target: CCR9

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human, Mouse

Clone: CBNH-016

Application*: E, WB, IF, IP

Mouse Anti-CCR9 Recombinant Antibody (CBYY-C0689) (CBMAB-C2025-YY)

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Target: CCR9

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human

Clone: CBYY-C0689

Application*: F, IF

Rabbit Anti-CCR9 Recombinant Antibody (CBFYC-1089) (CBMAB-C1146-FY)

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Target: CCR9

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human, Mouse, Rat

Clone: CBFYC-1089

Application*: F, WB, IF

Mouse Anti-CCR9 Recombinant Antibody (CBFYC-1088) (CBMAB-C1145-FY)

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Target: CCR9

Host: Mouse

Antibody Isotype: IgG2b, κ

Specificity: Human, Mouse, Rat

Clone: CBFYC-1088

Application*: WB, IP, IF, F

Rabbit Anti-CCR9 Recombinant Antibody (CBFYC-0468) (CBMAB-C0514-FY)

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Target: CCR9

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human, Mouse, Rat

Clone: CBFYC-0468

Application*: WB

Mouse Anti-CCR9 Recombinant Antibody (CBFYC-0205) (CBMAB-C0230-FY)

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Target: CCR9

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Mouse

Clone: CBFYC-0205

Application*: F

Mouse Anti-CCR9 Recombinant Antibody (882416) (CBMAB-C9003-LY)

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Target: CCR9

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Rat

Clone: 882416

Application*: F

Rat Anti-CCR9 Recombinant Antibody (7E7) (CBMAB-C8676-LY)

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Target: CCR9

Host: Rat

Antibody Isotype: IgG2b

Specificity: Mouse

Clone: 7E7

Application*: F, IF

Rat Anti-CCR9 Recombinant Antibody (242503) (CBMAB-C0715-LY)

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Target: CCR9

Host: Rat

Antibody Isotype: IgG2b

Specificity: Mouse

Clone: 242503

Application*: F

Mouse Anti-CCR9 Recombinant Antibody (112509) (CBMAB-C0204-LY)

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Target: CCR9

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human

Clone: 112509

Application*: F, IH, IC

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(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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