CCR9
CCR9 (C-C Motif Chemokine Receptor 9) is a Protein Coding gene. Diseases associated with CCR9 include Celiac Disease 1 and Cd45 Deficiency. Among its related pathways are Akt Signaling and Allograft rejection. Gene Ontology (GO) annotations related to this gene include G-protein coupled receptor activity and C-C chemokine receptor activity. An important paralog of this gene is CCR7.
Full Name
C-C Motif Chemokine Receptor 9
Function
Receptor for chemokine SCYA25/TECK. Subsequently transduces a signal by increasing the intracellular calcium ions level.
(Microbial infection) Alternative coreceptor with CD4 for HIV-1 infection.
(Microbial infection) Alternative coreceptor with CD4 for HIV-1 infection.
Biological Process
Calcium-mediated signaling Source: GO_Central
CD8-positive, gamma-delta intraepithelial T cell differentiation Source: Ensembl
Cell chemotaxis Source: GO_Central
Cellular defense response Source: ProtInc
Chemotaxis Source: ProtInc
G protein-coupled receptor signaling pathway Source: Reactome
Immune response Source: GO_Central
Positive regulation of cytosolic calcium ion concentration Source: GO_Central
Viral process Source: UniProtKB-KW
CD8-positive, gamma-delta intraepithelial T cell differentiation Source: Ensembl
Cell chemotaxis Source: GO_Central
Cellular defense response Source: ProtInc
Chemotaxis Source: ProtInc
G protein-coupled receptor signaling pathway Source: Reactome
Immune response Source: GO_Central
Positive regulation of cytosolic calcium ion concentration Source: GO_Central
Viral process Source: UniProtKB-KW
Cellular Location
Cell membrane
Topology
Extracellular: 1-48
Helical: 49-74
Cytoplasmic: 75-85
Helical: 86-109
Extracellular: 110-120
Helical: 121-150
Cytoplasmic: 151-159
Helical: 160-185
Extracellular: 186-208
Helical: 209-243
Cytoplasmic: 244-248
Helical: 249-283
Extracellular: 284-290
Helical: 291-321
Cytoplasmic: 322-369
Helical: 49-74
Cytoplasmic: 75-85
Helical: 86-109
Extracellular: 110-120
Helical: 121-150
Cytoplasmic: 151-159
Helical: 160-185
Extracellular: 186-208
Helical: 209-243
Cytoplasmic: 244-248
Helical: 249-283
Extracellular: 284-290
Helical: 291-321
Cytoplasmic: 322-369
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Anti-CCR9 antibodies
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Target: CCR9
Host: Mouse
Antibody Isotype: IgG2
Specificity: Human
Clone: 6D10
Application*: F, IH
Target: CCR9
Host: Human
Antibody Isotype: IgG1
Specificity: Human
Clone: 8H4
Application*: E
Target: CCR9
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: 4G2
Application*: E, IF
Target: CCR9
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse
Clone: CBNH-016
Application*: E, WB, IF, IP
Target: CCR9
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBYY-C0689
Application*: F, IF
Target: CCR9
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: CBFYC-1089
Application*: F, WB, IF
Target: CCR9
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human, Mouse, Rat
Clone: CBFYC-1088
Application*: WB, IP, IF, F
Target: CCR9
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse, Rat
Clone: CBFYC-0468
Application*: WB
Target: CCR9
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: CBFYC-0205
Application*: F
Target: CCR9
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Rat
Clone: 882416
Application*: F
Target: CCR9
Host: Rat
Antibody Isotype: IgG2b
Specificity: Mouse
Clone: 7E7
Application*: F, IF
Target: CCR9
Host: Rat
Antibody Isotype: IgG2b
Specificity: Mouse
Clone: 242503
Application*: F
Target: CCR9
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 112509
Application*: F, IH, IC
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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