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CERS4

CERS4 (Ceramide Synthase 4) is a Protein Coding gene. Among its related pathways are Metabolism and Sphingolipid metabolism. Gene Ontology (GO) annotations related to this gene include sphingosine N-acyltransferase activity. An important paralog of this gene is CERS2.
Full Name
Ceramide Synthase 4
Function
Ceramide synthase that catalyzes formation of ceramide from sphinganine and acyl-CoA substrates, with high selectivity toward long and very-long chains (C18:0-C22:0) as acyl donor.
Biological Process
Ceramide biosynthetic process Source: UniProtKB
Sphingolipid biosynthetic process Source: Reactome
Cellular Location
Endoplasmic reticulum membrane
Topology
Lumenal: 1-31
Helical: 32-52
Helical: 140-160
Helical: 179-199
Helical: 209-229
Helical: 260-280
Helical: 304-324
Cytoplasmic: 325-394
PTM
Phosphorylated at the C-terminus by CK2.
N-glycosylated.

Anti-CERS4 antibodies

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Mouse Anti-CERS4 Recombinant Antibody (CBYJL-101) (CBMAB-L0157-YJ)

Datasheet SDS
Target: CERS4
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBYJL-101
Application*: WB, E, IF

Mouse Anti-CERS4 Recombinant Antibody (CBYJL-100) (CBMAB-L0156-YJ)

Datasheet SDS
Target: CERS4
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBYJL-100
Application*: E, WB

Mouse Anti-CERS4 Recombinant Antibody (CBYJL-099) (CBMAB-L0155-YJ)

Datasheet SDS
Target: CERS4
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBYJL-099
Application*: E, IF, WB

Mouse Anti-CERS4 Recombinant Antibody (CBYJL-097) (CBMAB-L0153-YJ)

Datasheet SDS
Target: CERS4
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBYJL-097
Application*: E, WB

Mouse Anti-CERS4 Recombinant Antibody (CBYJL-095) (CBMAB-L0151-YJ)

Datasheet SDS
Target: CERS4
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBYJL-095
Application*: E

Mouse Anti-CERS4 Recombinant Antibody (7D5) (CBMAB-A4870-LY)

Datasheet SDS
Target: CERS4
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 7D5
Application*: SE, E

Mouse Anti-CERS4 Recombinant Antibody (2G6) (CBMAB-A4867-LY)

Datasheet SDS
Target: CERS4
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 2G6
Application*: WB, E

Mouse Anti-CERS4 Recombinant Antibody (2C12) (CBMAB-A4866-LY)

Datasheet SDS
Target: CERS4
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 2C12
Application*: WB, E

Mouse Anti-CERS4 Recombinant Antibody (7D5) (CBMAB-C8632-LY)

Datasheet SDS
Target: CERS4
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 7D5
Application*: E, IF, WB
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)
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