CERS4

CERS4 (Ceramide Synthase 4) is a Protein Coding gene. Among its related pathways are Metabolism and Sphingolipid metabolism. Gene Ontology (GO) annotations related to this gene include sphingosine N-acyltransferase activity. An important paralog of this gene is CERS2.
Full Name
Ceramide Synthase 4
Function
Ceramide synthase that catalyzes formation of ceramide from sphinganine and acyl-CoA substrates, with high selectivity toward long and very-long chains (C18:0-C22:0) as acyl donor.
Biological Process
Ceramide biosynthetic process Source: UniProtKB
Sphingolipid biosynthetic process Source: Reactome
Cellular Location
Endoplasmic reticulum membrane
Topology
Lumenal: 1-31
Helical: 32-52
Helical: 140-160
Helical: 179-199
Helical: 209-229
Helical: 260-280
Helical: 304-324
Cytoplasmic: 325-394
PTM
Phosphorylated at the C-terminus by CK2.
N-glycosylated.
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Anti-CERS4 antibodies

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Mouse Anti-CERS4 Recombinant Antibody (CBYJL-101) (CBMAB-L0157-YJ)

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Target: CERS4
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBYJL-101
Application*: E, WB
Datasheet SDS

Mouse Anti-CERS4 Recombinant Antibody (CBYJL-100) (CBMAB-L0156-YJ)

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Target: CERS4
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBYJL-100
Application*: E, WB
Datasheet SDS

Mouse Anti-CERS4 Recombinant Antibody (CBYJL-099) (CBMAB-L0155-YJ)

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Target: CERS4
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBYJL-099
Application*: WB, E
Datasheet SDS

Mouse Anti-CERS4 Recombinant Antibody (CBYJL-097) (CBMAB-L0153-YJ)

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Target: CERS4
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBYJL-097
Application*: E, IF, WB
Datasheet SDS

Mouse Anti-CERS4 Recombinant Antibody (CBYJL-095) (CBMAB-L0151-YJ)

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Target: CERS4
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBYJL-095
Application*: WB, IP, IF, E
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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