CST7
CST7 (Cystatin F) is a Protein Coding gene. Diseases associated with CST7 include Aicardi-Goutieres Syndrome. Gene Ontology (GO) annotations related to this gene include endopeptidase inhibitor activity and cysteine-type endopeptidase inhibitor activity.
Full Name
Cystatin F
Function
Inhibits papain and cathepsin L but with affinities lower than other cystatins. May play a role in immune regulation through inhibition of a unique target in the hematopoietic system.
Biological Process
Immune response Source: ProtInc
Inhibition of cysteine-type endopeptidase activity Source: GO_Central
Negative regulation of microglial cell activation Source: GO_Central
Negative regulation of peptidase activity Source: ARUK-UCL
Positive regulation of myelination Source: GO_Central
Inhibition of cysteine-type endopeptidase activity Source: GO_Central
Negative regulation of microglial cell activation Source: GO_Central
Negative regulation of peptidase activity Source: ARUK-UCL
Positive regulation of myelination Source: GO_Central
Cellular Location
Secreted; Cytoplasm
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Anti-CST7 antibodies
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Target: CST7
Sensitivity: 0.12 ng/mL
Detection Range: 0.3-90 ng/mL
Sample Type: Serum, Plasma, cell culture supernates
Specificity: Human
Assay Type: Sandwich
Reactivity: Human
Target: Cst7
Sensitivity: 0.025 ng/mL
Detection Range: 0.05-20 ng/mL
Sample Type: Serum, Plasma, cell culture supernates
Specificity: Mouse
Assay Type: Sandwich
Reactivity: Mouse
Target: CST7
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 1-144
Tag: hFc Tag
Target: CST7
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 1-145
Tag: His Tag
Target: CST7
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 1-145
Tag: hFc Tag
Target: CST7
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 1-145
Target: CST7
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBCNC-431
Application*: E
Target: CST7
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYC-2348
Application*: E
Target: CST7
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: C5060
Application*: WB
Target: CST7
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: C5040
Application*: E
Target: CST7
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: C4549
Application*: WB
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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