loading...

DCTN4

DCTN4 (Dynactin Subunit 4) is a Protein Coding gene. Diseases associated with DCTN4 include Cystic Fibrosis. Among its related pathways are COPI-independent Golgi-to-ER retrograde traffic and Transport to the Golgiand subsequent modification. Gene Ontology (GO) annotations related to this gene include protein N-terminus binding.

Full Name

dynactin 4

Function

Could have a dual role in dynein targeting and in ACTR1A/Arp1 subunit of dynactin pointed-end capping. Could be involved in ACTR1A pointed-end binding and in additional roles in linking dynein and dynactin to the cortical cytoskeleton.

Biological Process

Antigen processing and presentation of exogenous peptide antigen via MHC class II Source: Reactome
Endoplasmic reticulum to Golgi vesicle-mediated transport Source: Reactome

Cellular Location

Cytoskeleton; Centrosome; Stress fiber; Cell cortex; sarcomere. Has a punctate cytoplasmic distribution as well as centrosomal distribution typical of dynactin (PubMed:10671518). Overexpression in cultured mammalian cells revealed colocalization with cortical actin, stress fibers, and focal adhesion sites, sites of potential interaction between microtubules and the cell cortex (By similarity). In skeletal muscles, costamere localization requires the presence of ANK2 (By similarity).

View more

Anti-DCTN4 antibodies

+ Filters

Loading...

Human DCTN4 ELISA Kit (V2LY-0626-LY3337)

Compare

Target: DCTN4

Sensitivity: 0.0056 ng/mL

Detection Range: 0.01-2 ng/mL

Sample Type: Serum, Plasma, cell culture supernates

Specificity: Human

Assay Type: Sandwich

Reactivity: Human

Mouse Anti-DCTN4 Recombinant Antibody (CBT4670) (V2LY-0625-LY993)

Compare

Target: DCTN4

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human, Mouse

Clone: CBT4670

Application*: WB, IH, IC, F

Mouse Anti-DCTN4 Recombinant Antibody (CBT4005) (V2LY-0625-LY992)

Compare

Target: DCTN4

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBT4005

Application*: WB, IH, IC, F

Mouse Anti-DCTN4 Recombinant Antibody (CBYCD-189) (V2LY-0125-LY1254)

Compare

Target: DCTN4

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human, Mouse, Rat

Clone: CBYCD-189

Application*: WB, IP, IF, E, P

Mouse Anti-DCTN4 Recombinant Antibody (9j47) (V2LY-0125-LY1253)

Compare

Target: DCTN4

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human, Mouse, Rat

Clone: 9j47

Application*: WB, IP, IF, E, P

Mouse Anti-DCTN4 Recombinant Antibody (D0416) (V2LY-0125-LY1252)

Compare

Target: DCTN4

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human, Mouse

Clone: D0416

Application*: E, IF, P, WB, F

More Infomation

Submit A Review

Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

Submit A Review

Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

Hot products

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

online inquiry

Online Inquiry