EEF1D

This gene encodes a subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This subunit, delta, functions as guanine nucleotide exchange factor. It is reported that following HIV-1 infection, this subunit interacts with HIV-1 Tat. This interaction results in repression of translation of host cell proteins and enhanced translation of viral proteins. Several alternatively spliced transcript variants encoding multiple isoforms have been found for this gene. Related pseudogenes have been defined on chromosomes 1, 6, 7, 9, 11, 13, 17, 19.[provided by RefSeq, Aug 2010]
Full Name
Eukaryotic Translation Elongation Factor 1 Delta
Research Area
Isoform 1:
EF-1-beta and EF-1-delta stimulate the exchange of GDP bound to EF-1-alpha to GTP, regenerating EF-1-alpha for another round of transfer of aminoacyl-tRNAs to the ribosome.

Isoform 2:
Regulates induction of heat-shock-responsive genes through association with heat shock transcription factors and direct DNA-binding at heat shock promoter elements (HSE).
Biological Process
Cellular response to ionizing radiation Source: UniProtKB
mRNA transcription Source: UniProtKB
Positive regulation of I-kappaB kinase/NF-kappaB signaling Source: UniProtKB
Regulation of cell death Source: UniProtKB
Translational elongation Source: GO_Central
Cellular Location
Isoform 2: Nucleus
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Anti-EEF1D antibodies

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Mouse Anti-EEF1D Recombinant Antibody (CF143) (CBMAB-FT337LY)

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Target: EEF1D
Host: Mouse
Antibody Isotype: IgG3, κ
Specificity: Human, Mouse, Rat
Clone: CF143
Application*: WB, IP, IF, E
Datasheet SDS

Mouse Anti-EEF1D Recombinant Antibody (98) (CBMAB-AP1985LY)

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Target: EEF1D
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Rat
Clone: 98
Application*: F, IF, P, WB
Datasheet SDS

Mouse Anti-EEF1D Recombinant Antibody (440) (CBMAB-AP1984LY)

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Target: EEF1D
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Rat
Clone: 440
Application*: IP, IF, IH, WB
Datasheet SDS

Mouse Anti-EEF1D Recombinant Antibody (CBFYE-0465) (CBMAB-E0803-FY)

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Target: EEF1D
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human, Mouse, Rat
Clone: CBFYE-0465
Application*: IP, WB
Datasheet SDS

Mouse Anti-EEF1D Recombinant Antibody (CF144) (V2LY-0425-LY1454)

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Target: EEF1D
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse, Rat
Clone: CF144
Application*: WB, IP, IF, E
Datasheet SDS

Mouse Anti-EEF1D Recombinant Antibody (4B12) (V2LY-0425-LY1452)

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Target: EEF1D
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 4B12
Application*: WB, E, IF
Datasheet SDS

Mouse Anti-EEF1D Recombinant Antibody (CBFYE-0464) (V2LY-0425-LY1450)

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Target: EEF1D
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse
Clone: CBFYE-0464
Application*: E, IH, IF
Datasheet SDS

Mouse Anti-EEF1D Recombinant Antibody (CBFYE-0463) (V2LY-0425-LY1449)

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Target: EEF1D
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse
Clone: CBFYE-0463
Application*: E, WB, IH
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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