EFEMP1

This gene encodes a member of the fibulin family of extracellular matrix glycoproteins. Like all members of this family, the encoded protein contains tandemly repeated epidermal growth factor-like repeats followed by a C-terminus fibulin-type domain. This gene is upregulated in malignant gliomas and may play a role in the aggressive nature of these tumors. Mutations in this gene are associated with Doyne honeycomb retinal dystrophy. Alternatively spliced transcript variants that encode the same protein have been described.[provided by RefSeq, Nov 2009]
Full Name
EGF Containing Fibulin Extracellular Matrix Protein 1
Research Area
Binds EGFR, the EGF receptor, inducing EGFR autophosphorylation and the activation of downstream signaling pathways. May play a role in cell adhesion and migration. May function as a negative regulator of chondrocyte differentiation. In the olfactory epithelium, it may regulate glial cell migration, differentiation and the ability of glial cells to support neuronal neurite outgrowth.
Biological Process
Camera-type eye development Source: UniProtKB
Embryonic eye morphogenesis Source: UniProtKB
Epidermal growth factor receptor signaling pathway Source: UniProtKB
Negative regulation of chondrocyte differentiation Source: UniProtKB
Peptidyl-tyrosine phosphorylation Source: UniProtKB
Post-embryonic eye morphogenesis Source: UniProtKB
Regulation of transcription, DNA-templated Source: UniProtKB
Visual perception Source: ProtInc
Cellular Location
Extracellular space; Extracellular matrix. Localizes to the lamina propria underneath the olfactory epithelium.
Involvement in disease
Doyne honeycomb retinal dystrophy (DHRD):
Autosomal dominant disease characterized by yellow-white deposits known as drusen that accumulate beneath the retinal pigment epithelium.
View more

Anti-EFEMP1 antibodies

+ Filters
Loading...

Mouse Anti-EFEMP1 Recombinant Antibody (CAP744) (CBMAB-AP2214LY)

Go to compareCompare
Target: EFEMP1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse, Rat
Clone: CAP744
Application*: WB, IP, IF, P
Datasheet SDS

Mouse Anti-EFEMP1 Recombinant Antibody (1D9) (CBMAB-F2762-CQ)

Go to compareCompare
Target: EFEMP1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 1D9
Application*: WB, E, IP
Datasheet SDS

Mouse Anti-EFEMP1 Recombinant Antibody (CBXF-0122) (CBMAB-F2654-CQ)

Go to compareCompare
Target: EFEMP1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBXF-0122
Application*: WB, IP, IF, E, P
Datasheet SDS

Mouse Efemp1 ELISA Kit (V2LY-0626-LY5883)

Go to compareCompare
Target: Efemp1
Sensitivity: 0.0099 ng/mL
Detection Range: 0.02-4.5 ng/mL
Sample Type: Serum, Plasma, cell culture supernates
Specificity: Mouse
Assay Type: Sandwich
Reactivity: Mouse
Datasheet SDS

Human EFEMP1 ELISA Kit (V2LY-0626-LY4532)

Go to compareCompare
Target: EFEMP1
Sensitivity: 0.33 ng/mL
Detection Range: 0.5-200 ng/mL
Sample Type: Serum, Plasma, cell culture supernates
Specificity: Human
Assay Type: Sandwich
Reactivity: Human
Datasheet SDS

Mouse Anti-EFEMP1 Recombinant Antibody (CBXF-0123) (V2LY-0425-LY1480)

Go to compareCompare
Target: EFEMP1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBXF-0123
Application*: WB
Datasheet SDS

Mouse Anti-EFEMP1 Recombinant Antibody (CBFYE-0474) (V2LY-0425-LY1479)

Go to compareCompare
Target: EFEMP1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBFYE-0474
Application*: WB
Datasheet SDS

Rabbit Anti-EFEMP1 Recombinant Antibody (EG1036) (CBMAB-EN1221-LY)

Go to compareCompare
Target: EFEMP1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse
Clone: EG1036
Application*: WB, IF, P
Datasheet SDS
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

Hot products Hot products

For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
online inquiry
Online Inquiry

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.