ELAVL3
A member of the ELAVL protein family, ELAV-like 3 is a neural-specific RNA-binding protein which contains three RNP-type RNA recognition motifs. The observation that ELAVL3 is one of several Hu antigens (neuronal-specific RNA-binding proteins) recognized by the anti-Hu serum antibody present in sera from patients with paraneoplastic encephalomyelitis and sensory neuronopathy (PEM/PSN) suggests it has a role in neurogenesis. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Full Name
Elav Like Rna Binding Protein 3
Research Area
RNA-binding protein that binds to AU-rich element (ARE) sequences of target mRNAs, including VEGF mRNA (PubMed:10710437).
May also bind poly-A tracts via RRM 3 (By similarity).
May be involved in neuronal differentiation and maintenance (By similarity).
Plays a role in the stabilization of GAP43 mRNA and in spatial learning (By similarity).
May also bind poly-A tracts via RRM 3 (By similarity).
May be involved in neuronal differentiation and maintenance (By similarity).
Plays a role in the stabilization of GAP43 mRNA and in spatial learning (By similarity).
Biological Process
Cell differentiation Source: UniProtKB-KW
Nervous system development Source: UniProtKB-KW
Nervous system development Source: UniProtKB-KW
Cellular Location
Ribonucleoprotein complex
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Anti-ELAVL3 antibodies
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Target: ELAVL3
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Chicken, Human, Zebrafish, Mouse, Rat
Clone: CBFYE-0764
Application*: WB, IF, E, P, F
Target: ELAVL3
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse, Rat
Clone: 16A11
Application*: WB, IP, IF, E
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot

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