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EXOC4

The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. The complex is also essential for the biogenesis of epithelial cell surface polarity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq]
Full Name
exocyst complex component 4
Research Area
Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
Biological Process
Chemical synaptic transmission Source: GO_Central
Exocytosis Source: GO_Central
Golgi to plasma membrane transport Source: GO_Central
Paraxial mesoderm formation Source: Ensembl
Protein transport Source: UniProtKB-KW
Regulation of macroautophagy Source: ParkinsonsUK-UCL
Vesicle docking involved in exocytosis Source: InterPro
Vesicle tethering involved in exocytosis Source: InterPro
Cellular Location
Midbody ring; Cell projection. Colocalizes with CNTRL/centriolin at the midbody ring (PubMed:16213214). Localizes at the leading edge of migrating cells (By similarity).
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Anti-EXOC4 antibodies

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Mouse Anti-EXOC4 Recombinant Antibody (4F1) (CBMAB-A2749-LY)

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Target: EXOC4
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human, Mouse, Rat
Clone: 4F1
Application*: WB, E
Datasheet SDS

Mouse Anti-EXOC4 Recombinant Antibody (CBXS-2046) (CBMAB-S4813-CQ)

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Target: EXOC4
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Rat, Cattle, Dog, Chicken, Rabbit, Sheep
Clone: CBXS-2046
Application*: WB, IP, IF, IH
Datasheet SDS

Mouse Anti-EXOC4 Recombinant Antibody (CBXS-3726) (CBMAB-S1001-CQ)

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Target: EXOC4
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Mouse, Rat
Clone: CBXS-3726
Application*: WB, IP, IF, E
Datasheet SDS

Mouse Anti-EXOC4 Recombinant Antibody (CBFYE-1385) (CBMAB-E2003-FY)

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Target: EXOC4
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human, Mouse, Rat
Clone: CBFYE-1385
Application*: E, WB, IP
Datasheet SDS

Mouse Anti-EXOC4 Recombinant Antibody (CBFYE-0282) (CBMAB-E0562-FY)

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Target: EXOC4
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Rat
Clone: CBFYE-0282
Application*: WB
Datasheet SDS
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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