FAM19A1

FAM19A1 is a member of the TAFA family which is composed of five highly homologous genes that encode small secreted proteins. These proteins contain conserved cysteine residues at fixed positions, and are distantly related to MIP-1alpha, a member of the CC-chemokine family. The TAFA proteins are predominantly expressed in specific regions of the brain, and are postulated to play a role as brain-specific chemokines or neurokines that act as regulators of immune and nervous cells.

Family With Sequence Similarity 19 Member A1, C-C Motif Chemokine Like

Regulatory factor which is ligand for CMKLR2 and is involved in the modulation of neural stem-cell proliferation and differentiation.

Neuroblast differentiation Source: UniProtKB
Regulation of neuroblast proliferation Source: UniProtKB
Regulation of signaling receptor activity Source: UniProtKB

Secreted