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FAM19A3

FAM19A3 is a member of the TAFA family which is composed of five highly homologous genes that encode small secreted proteins. These proteins contain conserved cysteine residues at fixed positions, and are distantly related to MIP-1alpha, a member of the CC-chemokine family. The TAFA proteins are predominantly expressed in specific regions of the brain, and are postulated to play a role as brain-specific chemokines or neurokines, that act as regulators of immune and nervous cells. Alternatively spliced transcript variants encoding multiple isoforms have been observed for FAM19A3.

Full Name

Family With Sequence Similarity 19 Member A3, C-C Motif Chemokine Like

Research Area

Plays a role in the regulation of microglia polarization.

Biological Process

Negative regulation of microglial cell activation Source: UniProtKB
Neuroblast differentiation Source: GO_Central
Positive regulation of microglial cell activation Source: UniProtKB
Regulation of neuroblast proliferation Source: GO_Central

Cellular Location

Secreted

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Anti-FAM19A3 antibodies

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Mouse Anti-FAM19A3 Recombinant Antibody (CBYJT-1276) (CBMAB-T0291-YJ)

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Target: FAM19A3

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: CBYJT-1276

Application*: WB, F

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For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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