Mouse Anti-FAM19A3 Recombinant Antibody (CBYJT-1276) (CBMAB-T0291-YJ)

Name: Mouse Anti-FAM19A3 Recombinant Antibody (CBYJT-1276)
SKU: CBMAB-T0291-YJ
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

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Basic Information

Host Animal

Mouse

Clone

CBYJT-1276

Application

WB, FC

Immunogen

E. coli-derived recombinant human TAFA3/FAM19A3 (Ala31-Arg133).

Host Species

Mouse

Specificity

Human

Antibody Isotype

IgG2b

Clonality

Monoclonal Antibody

Application Notes

The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Application	Note
WB	1 μg/ml
FC	2.5 μg/10^6 cells

Formulations & Storage [For reference only, actual COA shall prevail!]

Format

Lyophilized

Buffer

PBS, trehalose

Preservative

None

Concentration

Batch dependent

Purity

> 95% Purity determined by SDS-PAGE.

Storage

Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freezethaw cycles.

Epitope

aa 31-133

More Infomation

Target

Full Name

Family With Sequence Similarity 19 Member A3, C-C Motif Chemokine Like

Introduction

FAM19A3 is a member of the TAFA family which is composed of five highly homologous genes that encode small secreted proteins. These proteins contain conserved cysteine residues at fixed positions, and are distantly related to MIP-1alpha, a member of the CC-chemokine family. The TAFA proteins are predominantly expressed in specific regions of the brain, and are postulated to play a role as brain-specific chemokines or neurokines, that act as regulators of immune and nervous cells. Alternatively spliced transcript variants encoding multiple isoforms have been observed for FAM19A3.

Entrez Gene ID

284467

UniProt ID

Q7Z5A8

Alternative Names

Family With Sequence Similarity 19 Member A3, C-C Motif Chemokine Like; Family With Sequence Similarity 19 (Chemokine (C-C Motif)-Like), Member A3; Chemokine-Like Protein TAFA-3; TAFA3; Protein FAM19A3; TAFA-3

Research Area

Plays a role in the regulation of microglia polarization.

Biological Process

Negative regulation of microglial cell activation Source: UniProtKB
Neuroblast differentiation Source: GO_Central
Positive regulation of microglial cell activation Source: UniProtKB
Regulation of neuroblast proliferation Source: GO_Central

Cellular Location

Secreted

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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