FOXJ2
FOXJ2 (Forkhead Box J2) is a Protein Coding gene. Diseases associated with FOXJ2 include Cardiomyopathy, Familial Hypertrophic, 3. Gene Ontology (GO) annotations related to this gene include DNA binding transcription factor activity and RNA polymerase II proximal promoter sequence-specific DNA binding. An important paralog of this gene is FOXJ3.
Full Name
FOXJ2
Function
Isoform FOXJ2.L:
Transcriptional activator. Able to bind to two different type of DNA binding sites. More effective than isoform FOXJ2.S in transcriptional activation (PubMed:10777590, PubMed:10966786).
Plays an important role in spermatogenesis, especially in spermatocyte meiosis (By similarity).
Isoform FOXJ2.S:
Transcriptional activator.
Transcriptional activator. Able to bind to two different type of DNA binding sites. More effective than isoform FOXJ2.S in transcriptional activation (PubMed:10777590, PubMed:10966786).
Plays an important role in spermatogenesis, especially in spermatocyte meiosis (By similarity).
Isoform FOXJ2.S:
Transcriptional activator.
Biological Process
Cell differentiation Source: UniProtKB-KW
Male meiosis I Source: UniProtKB
Negative regulation of angiogenesis Source: BHF-UCL
Negative regulation of blood vessel endothelial cell differentiation Source: BHF-UCL
Positive regulation of transcription, DNA-templated Source: UniProtKB
Positive regulation of transcription by RNA polymerase II Source: NTNU_SB
Positive regulation of vascular associated smooth muscle cell proliferation Source: BHF-UCL
Regulation of transcription by RNA polymerase II Source: GO_Central
Spermatogenesis Source: UniProtKB
Male meiosis I Source: UniProtKB
Negative regulation of angiogenesis Source: BHF-UCL
Negative regulation of blood vessel endothelial cell differentiation Source: BHF-UCL
Positive regulation of transcription, DNA-templated Source: UniProtKB
Positive regulation of transcription by RNA polymerase II Source: NTNU_SB
Positive regulation of vascular associated smooth muscle cell proliferation Source: BHF-UCL
Regulation of transcription by RNA polymerase II Source: GO_Central
Spermatogenesis Source: UniProtKB
Cellular Location
Nucleus
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Anti-FOXJ2 antibodies
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Target: FOXJ2
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: 1C3
Application*: WB, E
Target: FOXJ2
Host: Mouse
Antibody Isotype: IgM, κ
Specificity: Human, Mouse, Rat
Clone: CBXF-3157
Application*: WB, IP, IF, E
Target: FOXJ2
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: CBXF-1779
Application*: WB, IP, E
Target: FOXJ2
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human, Mouse, Chicken
Clone: 1D3
Application*: IP
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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