FSD1

This gene encodes a centrosome associated protein that is characterized by an N-terminal coiled-coil region downstream of B-box (BBC) domain, a central fibronectin type III domain, and a C-terminal repeats in splA and RyR (SPRY) domain. The encoded protein associates with a subset of microtubules and may be involved in the stability and organization of microtubules during cytokinesis. [provided by RefSeq]

fibronectin type III and SPRY domain containing 1

May be involved in microtubule organization and stabilization.

Cell cycle Source: UniProtKB-KW
Cell division Source: UniProtKB-KW
Cytoplasmic microtubule organization Source: UniProtKB
Regulation of cell division Source: UniProtKB
Regulation of cytokinesis Source: UniProtKB
Regulation of mitotic spindle organization Source: UniProtKB

Centrosome; Cytoplasm; Nucleus; Cleavage furrow. Cell-cycle-dependent association with the centrosome. Colocalizes with a subpopulation of microtubules. Does not associates with microtubules during mitosis but reassociates with microtubules during cytokinesis. Localizes to the central portions of a small subset of microtubules in interphase cells and a subpopulation of microtubules in the cleavage furrow, not present in the mitotic spindle.