FSD1
This gene encodes a centrosome associated protein that is characterized by an N-terminal coiled-coil region downstream of B-box (BBC) domain, a central fibronectin type III domain, and a C-terminal repeats in splA and RyR (SPRY) domain. The encoded protein associates with a subset of microtubules and may be involved in the stability and organization of microtubules during cytokinesis. [provided by RefSeq]
Full Name
fibronectin type III and SPRY domain containing 1
Function
May be involved in microtubule organization and stabilization.
Biological Process
Cell cycle Source: UniProtKB-KW
Cell division Source: UniProtKB-KW
Cytoplasmic microtubule organization Source: UniProtKB
Regulation of cell division Source: UniProtKB
Regulation of cytokinesis Source: UniProtKB
Regulation of mitotic spindle organization Source: UniProtKB
Cell division Source: UniProtKB-KW
Cytoplasmic microtubule organization Source: UniProtKB
Regulation of cell division Source: UniProtKB
Regulation of cytokinesis Source: UniProtKB
Regulation of mitotic spindle organization Source: UniProtKB
Cellular Location
Centrosome; Cytoplasm; Nucleus; Cleavage furrow. Cell-cycle-dependent association with the centrosome. Colocalizes with a subpopulation of microtubules. Does not associates with microtubules during mitosis but reassociates with microtubules during cytokinesis. Localizes to the central portions of a small subset of microtubules in interphase cells and a subpopulation of microtubules in the cleavage furrow, not present in the mitotic spindle.
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Anti-FSD1 antibodies
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Target: FSD1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 1G3
Application*: IP, E
Target: FSD1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBXF-3712
Application*: E, IP, WB
Target: FSD1
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBXF-0918
Application*: E, IP
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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