FST

Follistatin is a single-chain gonadal protein that specifically inhibits follicle-stimulating hormone release. The single FST gene encodes two isoforms, FST317 and FST344 containing 317 and 344 amino acids respectively, resulting from alternative splicing of the precursor mRNA. In a study in which 37 candidate genes were tested for linkage and association with polycystic ovary syndrome (PCOS) or hyperandrogenemia in 150 families, evidence was found for linkage between PCOS and follistatin. [provided by RefSeq, Jul 2008]
Full Name
Follistatin
Function
Binds directly to activin and functions as an activin antagonist. Specific inhibitor of the biosynthesis and secretion of pituitary follicle stimulating hormone (FSH).
Biological Process
BMP signaling pathway Source: Ensembl
Cell differentiation Source: GO_Central
Female gonad development Source: Ensembl
Gamete generation Source: Ensembl
Hair follicle morphogenesis Source: Ensembl
Hematopoietic progenitor cell differentiation Source: UniProtKB
Keratinocyte proliferation Source: Ensembl
Negative regulation of activin receptor signaling pathway Source: UniProtKB
Negative regulation of cell differentiation Source: Ensembl
Negative regulation of transcription by RNA polymerase II Source: UniProtKB
Odontogenesis of dentin-containing tooth Source: Ensembl
Pattern specification process Source: Ensembl
Positive regulation of hair follicle development Source: MGI
Regulation of BMP signaling pathway Source: GO_Central
Skeletal system development Source: Ensembl
Cellular Location
Secreted
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Anti-FST antibodies

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Mouse Anti-FST Recombinant Antibody (1689) (CBMAB-AP2403LY)

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Target: FST
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human, Mouse
Clone: 1689
Application*: ELISA, IF, IHC, WB
Datasheet SDS

Mouse Anti-FST Recombinant Antibody (4B11) (CBMAB-A3185-LY)

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Target: FST
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 4B11
Application*: WB, E
Datasheet SDS

Recombinant Mouse Anti-FST Recombinant Antibody (29/9) (CBMAB-XB0473-YC)

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Target: FST
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 29/9
Application*: E
Datasheet SDS

Mouse Anti-FST Recombinant Antibody (CBXF-1689) (CBMAB-F4144-CQ)

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Target: FST
Host: Mouse
Antibody Isotype: IgG2
Specificity: Human
Clone: CBXF-1689
Application*: IH, WB
Datasheet SDS

Mouse Anti-FST (AA 1-344) Recombinant Antibody (CBXF-3212) (CBMAB-F3907-CQ)

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Target: FST
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBXF-3212
Application*: E, WB
Datasheet SDS

Mouse Anti-FST Recombinant Antibody (CBXF-3211) (CBMAB-F3906-CQ)

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Target: FST
Host: Mouse
Antibody Isotype: IgM, κ
Specificity: Human
Clone: CBXF-3211
Application*: E, WB
Datasheet SDS

Mouse Anti-FST Recombinant Antibody (CBXF-3210) (CBMAB-F3905-CQ)

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Target: FST
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXF-3210
Application*: E, IH, WB
Datasheet SDS

Mouse Anti-FST Recombinant Antibody (CBXF-1954) (CBMAB-F2792-CQ)

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Target: FST
Host: Mouse
Antibody Isotype: IgG2
Specificity: Human
Clone: CBXF-1954
Application*: WB, P
Datasheet SDS

Mouse Anti-FST Recombinant Antibody (CBXF-0933) (CBMAB-F2684-CQ)

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Target: FST
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse
Clone: CBXF-0933
Application*: E, WB, IF
Datasheet SDS

Mouse Anti-FST Recombinant Antibody (CBXF-0935) (CBMAB-F2484-CQ)

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Target: FST
Host: Mouse
Antibody Isotype: IgM, κ
Specificity: Human
Clone: CBXF-0935
Application*: E, WB
Datasheet SDS

Mouse Anti-FST (AA 30-429) Recombinant Antibody (CBXF-2183) (CBMAB-F1893-CQ)

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Target: FST
Host: Mouse
Antibody Isotype: IgG2
Specificity: Human
Clone: CBXF-2183
Application*: P, WB
Datasheet SDS

Mouse Anti-FST Recombinant Antibody (H10) (CBMAB-F1787-CQ)

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Target: FST
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: H10
Application*: E, P, WB
Datasheet SDS

Mouse Anti-FST Recombinant Antibody (17/2) (CBMAB-F1643-CQ)

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Target: FST
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 17/2
Application*: E, P, WB
Datasheet SDS

Mouse Anti-FST Recombinant Antibody (CBXF-2342) (CBMAB-F1481-CQ)

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Target: FST
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human, Mouse
Clone: CBXF-2342
Application*: E, WB, IH, IF
Datasheet SDS

Mouse Anti-FST Recombinant Antibody (CBXF-0936) (CBMAB-F1456-CQ)

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Target: FST
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBXF-0936
Application*: WB, IC, P, C, E
Datasheet SDS

Mouse Anti-FST Recombinant Antibody (CBXF-0934) (CBMAB-F0982-CQ)

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Target: FST
Host: Mouse
Antibody Isotype: IgM
Specificity: Human
Clone: CBXF-0934
Application*: WB, E
Datasheet SDS

Rabbit Anti-FST Recombinant Antibody (CBXF-1083) (CBMAB-F0981-CQ)

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Target: FST
Host: Rabbit
Antibody Isotype: IgG
Specificity: Rat, Human
Clone: CBXF-1083
Application*: WB
Datasheet SDS

Mouse Anti-FST Recombinant Antibody (CBXF-2677) (CBMAB-F0177-CQ)

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Target: FST
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBXF-2677
Application*: WB, IH
Datasheet SDS

Mouse Anti-FST Recombinant Antibody (CF174) (CBMAB-FT315LY)

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Target: FST
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse
Clone: CF174
Application*: ELISA, WB, IHC, IF
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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