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FST

Follistatin is a single-chain gonadal protein that specifically inhibits follicle-stimulating hormone release. The single FST gene encodes two isoforms, FST317 and FST344 containing 317 and 344 amino acids respectively, resulting from alternative splicing of the precursor mRNA. In a study in which 37 candidate genes were tested for linkage and association with polycystic ovary syndrome (PCOS) or hyperandrogenemia in 150 families, evidence was found for linkage between PCOS and follistatin. [provided by RefSeq, Jul 2008]
Full Name
Follistatin
Function
Binds directly to activin and functions as an activin antagonist. Specific inhibitor of the biosynthesis and secretion of pituitary follicle stimulating hormone (FSH).
Biological Process
BMP signaling pathway Source: Ensembl
Cell differentiation Source: GO_Central
Female gonad development Source: Ensembl
Gamete generation Source: Ensembl
Hair follicle morphogenesis Source: Ensembl
Hematopoietic progenitor cell differentiation Source: UniProtKB
Keratinocyte proliferation Source: Ensembl
Negative regulation of activin receptor signaling pathway Source: UniProtKB
Negative regulation of cell differentiation Source: Ensembl
Negative regulation of transcription by RNA polymerase II Source: UniProtKB
Odontogenesis of dentin-containing tooth Source: Ensembl
Pattern specification process Source: Ensembl
Positive regulation of hair follicle development Source: MGI
Regulation of BMP signaling pathway Source: GO_Central
Skeletal system development Source: Ensembl
Cellular Location
Secreted

Anti-FST antibodies

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Mouse Anti-FST Recombinant Antibody (CBXF-2677) (CBMAB-F0177-CQ)

Datasheet SDS
Target: FST
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBXF-2677
Application*: WB, IH

Rabbit Anti-FST Recombinant Antibody (CBXF-1083) (CBMAB-F0981-CQ)

Datasheet SDS
Target: FST
Host: Rabbit
Antibody Isotype: IgG
Specificity: Rat, Human
Clone: CBXF-1083
Application*: WB

Mouse Anti-FST Recombinant Antibody (CBXF-0934) (CBMAB-F0982-CQ)

Datasheet SDS
Target: FST
Host: Mouse
Antibody Isotype: IgM
Specificity: Human
Clone: CBXF-0934
Application*: WB, E

Mouse Anti-FST Recombinant Antibody (CBXF-0936) (CBMAB-F1456-CQ)

Datasheet SDS
Target: FST
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBXF-0936
Application*: WB, IC, P, C, E

Mouse Anti-FST Recombinant Antibody (CBXF-2342) (CBMAB-F1481-CQ)

Datasheet SDS
Target: FST
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human, Mouse
Clone: CBXF-2342
Application*: E, WB, IH, IF

Mouse Anti-FST Recombinant Antibody (17/2) (CBMAB-F1643-CQ)

Datasheet SDS
Target: FST
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 17/2
Application*: E, P, WB

Mouse Anti-FST Recombinant Antibody (H10) (CBMAB-F1787-CQ)

Datasheet SDS
Target: FST
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: H10
Application*: E, P, WB

Mouse Anti-FST (AA 30-429) Recombinant Antibody (CBXF-2183) (CBMAB-F1893-CQ)

Datasheet SDS
Target: FST
Host: Mouse
Antibody Isotype: IgG2
Specificity: Human
Clone: CBXF-2183
Application*: P, WB

Mouse Anti-FST Recombinant Antibody (CBXF-0935) (CBMAB-F2484-CQ)

Datasheet SDS
Target: FST
Host: Mouse
Antibody Isotype: IgM, κ
Specificity: Human
Clone: CBXF-0935
Application*: E, WB

Mouse Anti-FST Recombinant Antibody (CBXF-0933) (CBMAB-F2684-CQ)

Datasheet SDS
Target: FST
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse
Clone: CBXF-0933
Application*: E, WB, IF

Mouse Anti-FST Recombinant Antibody (CBXF-1954) (CBMAB-F2792-CQ)

Datasheet SDS
Target: FST
Host: Mouse
Antibody Isotype: IgG2
Specificity: Human
Clone: CBXF-1954
Application*: WB, P

Mouse Anti-FST Recombinant Antibody (CBXF-3210) (CBMAB-F3905-CQ)

Datasheet SDS
Target: FST
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBXF-3210
Application*: E, IH, WB

Mouse Anti-FST Recombinant Antibody (CBXF-3211) (CBMAB-F3906-CQ)

Datasheet SDS
Target: FST
Host: Mouse
Antibody Isotype: IgM, κ
Specificity: Human
Clone: CBXF-3211
Application*: E, WB

Mouse Anti-FST (AA 1-344) Recombinant Antibody (CBXF-3212) (CBMAB-F3907-CQ)

Datasheet SDS
Target: FST
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBXF-3212
Application*: E, WB

Mouse Anti-FST Recombinant Antibody (CBXF-1689) (CBMAB-F4144-CQ)

Datasheet SDS
Target: FST
Host: Mouse
Antibody Isotype: IgG2
Specificity: Human
Clone: CBXF-1689
Application*: IH, WB

Recombinant Mouse Anti-FST Recombinant Antibody (29/9) (CBMAB-XB0473-YC)

Datasheet SDS
Target: FST
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 29/9
Application*: E

Mouse Anti-FST Recombinant Antibody (4B11) (CBMAB-A3185-LY)

Datasheet SDS
Target: FST
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 4B11
Application*: WB, E

Mouse Anti-FST Recombinant Antibody (CF174) (CBMAB-FT315LY)

Datasheet SDS
Target: FST
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse
Clone: CF174
Application*: ELISA, WB, IHC, IF

Mouse Anti-FST Recombinant Antibody (1689) (CBMAB-AP2403LY)

Datasheet SDS
Target: FST
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human, Mouse
Clone: 1689
Application*: ELISA, IF, IHC, WB
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)
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