GAS1
Growth arrest-specific 1 plays a role in growth suppression. GAS1 blocks entry to S phase and prevents cycling of normal and transformed cells. Gas1 is a putative tumor suppressor gene.
Full Name
growth arrest specific 1
Function
Specific growth arrest protein involved in growth suppression. Blocks entry to S phase. Prevents cycling of normal and transformed cells.
Biological Process
Cell cycle Source: UniProtKB-KW
Cell fate commitment Source: UniProtKB
Cellular response to vascular endothelial growth factor stimulus Source: UniProtKB
Developmental growth Source: UniProtKB
Negative regulation of mitotic cell cycle Source: UniProtKB
Negative regulation of protein processing Source: UniProtKB
Regulation of apoptotic process Source: UniProtKB
Regulation of ER to Golgi vesicle-mediated transport Source: UniProtKB
Regulation of smoothened signaling pathway Source: UniProtKB
Cell fate commitment Source: UniProtKB
Cellular response to vascular endothelial growth factor stimulus Source: UniProtKB
Developmental growth Source: UniProtKB
Negative regulation of mitotic cell cycle Source: UniProtKB
Negative regulation of protein processing Source: UniProtKB
Regulation of apoptotic process Source: UniProtKB
Regulation of ER to Golgi vesicle-mediated transport Source: UniProtKB
Regulation of smoothened signaling pathway Source: UniProtKB
Cellular Location
Cell membrane
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Anti-GAS1 antibodies
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Target: GAS1
Host: Rat
Antibody Isotype: IgG2
Specificity: Human
Clone: 11C47
Application*: E, WB
Target: GAS1
Host: Rat
Antibody Isotype: IgG2a
Specificity: Human
Clone: 309325
Application*: WB
Target: GAS1
Host: Rat
Antibody Isotype: IgG2
Specificity: Human
Clone: G2118
Application*: WB, E
Target: GAS1
Host: Rat
Antibody Isotype: IgG2a
Specificity: Human, Mouse
Clone: G0207
Application*: WB, E
Target: GAS1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse
Clone: EG1285
Application*: WB: 1:500~1:1000 ELISA: 1:40000
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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