GPAT3
GPAT3 may encode the major GPAT isoform in adipocytes, and play an important role in adipogenesis.
Full Name
GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE 3
Function
Converts glycerol-3-phosphate to 1-acyl-sn-glycerol-3-phosphate (lysophosphatidic acid or LPA) by incorporating an acyl moiety at the sn-1 position of the glycerol backbone (PubMed:17170135).
Also converts LPA into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone (PubMed:19318427).
Also converts LPA into 1,2-diacyl-sn-glycerol-3-phosphate (phosphatidic acid or PA) by incorporating an acyl moiety at the sn-2 position of the glycerol backbone (PubMed:19318427).
Biological Process
CDP-diacylglycerol biosynthetic process Source: UniProtKB-UniPathway
Glycerol-3-phosphate metabolic process Source: Ensembl
Phosphatidic acid biosynthetic process Source: Reactome
Regulation of TOR signaling Source: UniProtKB
Triglyceride biosynthetic process Source: UniProtKB
Glycerol-3-phosphate metabolic process Source: Ensembl
Phosphatidic acid biosynthetic process Source: Reactome
Regulation of TOR signaling Source: UniProtKB
Triglyceride biosynthetic process Source: UniProtKB
Cellular Location
Endoplasmic reticulum membrane
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Anti-GPAT3 antibodies
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Target: GPAT3
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human, Mouse, Rat
Clone: CBYJL-213
Application*: E, IP, IF, WB
Target: GPAT3
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human, Mouse, Rat
Clone: CBYJL-212
Application*: E, IP, IF, WB
Target: GPAT3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBLG1-187
Application*: WB
Target: GPAT3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBLG1-1571
Application*: WB, IH
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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