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GPR87

This gene encodes a G protein-coupled receptor and is located in a cluster of G protein-couple receptor genes on chromosome 3. The encoded protein has been shown to be overexpressed in lung squamous cell carcinoma (PMID:18057535) and regulated by p53.

Full Name

G protein-coupled receptor 87

Function

Receptor for lysophosphatidic acid (LPA). Necessary for p53/TP53-dependent survival in response to DNA damage.

Biological Process

G protein-coupled receptor signaling pathway Source: GO_Central
Negative regulation of adenylate cyclase activity Source: InterPro

Cellular Location

Cell membrane

Topology

Extracellular: 1-47
Helical: 48-68
Cytoplasmic: 69-75
Helical: 76-96
Extracellular: 97-116
Helical: 117-137
Cytoplasmic: 138-159
Helical: 160-180
Extracellular: 181-208
Helical: 209-229
Cytoplasmic: 230-256
Helical: 257-277
Extracellular: 278-297
Helical: 298-318
Cytoplasmic: 319-358

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Anti-GPR87 antibodies

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Human Anti-GPR87 Recombinant Antibody (CBLG1-1647) (V2LY-0226-LY905)

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Target: GPR87

Host: Human

Antibody Isotype: IgG1

Specificity: Human

Clone: CBLG1-1647

Application*: F

Mouse Anti-GPR87 Recombinant Antibody (EG1410) (CBMAB-EN1689-LY)

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Target: GPR87

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: EG1410

Application*: E

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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