GPR87

This gene encodes a G protein-coupled receptor and is located in a cluster of G protein-couple receptor genes on chromosome 3. The encoded protein has been shown to be overexpressed in lung squamous cell carcinoma (PMID:18057535) and regulated by p53.
Full Name
G protein-coupled receptor 87
Function
Receptor for lysophosphatidic acid (LPA). Necessary for p53/TP53-dependent survival in response to DNA damage.
Biological Process
G protein-coupled receptor signaling pathway Source: GO_Central
Negative regulation of adenylate cyclase activity Source: InterPro
Cellular Location
Cell membrane
Topology
Extracellular: 1-47
Helical: 48-68
Cytoplasmic: 69-75
Helical: 76-96
Extracellular: 97-116
Helical: 117-137
Cytoplasmic: 138-159
Helical: 160-180
Extracellular: 181-208
Helical: 209-229
Cytoplasmic: 230-256
Helical: 257-277
Extracellular: 278-297
Helical: 298-318
Cytoplasmic: 319-358
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Anti-GPR87 antibodies

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Human Anti-GPR87 Recombinant Antibody (CBLG1-1647) (V2LY-0226-LY905)

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Target: GPR87
Host: Human
Antibody Isotype: IgG1
Specificity: Human
Clone: CBLG1-1647
Application*: F
Datasheet SDS

Mouse Anti-GPR87 Recombinant Antibody (EG1410) (CBMAB-EN1689-LY)

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Target: GPR87
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: EG1410
Application*: E
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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