GTF2A1L
The assembly and stability of the RNA polymerase II transcription pre-initiation complex on a eukaryotic core promoter involve the effects of transcription factor IIA (TFIIA) on the interaction between TATA-binding protein (TBP) and DNA. This gene encodes a germ cell-specific counterpart of the large (alpha/beta) subunit of general transcription factor TFIIA that is able to stabilize the binding of TBP to DNA and may be uniquely important to testis biology. Alternative splicing for this locus has been observed and two variants, encoding distinct isoforms, have been identified. Co-transcription of this gene and the neighboring upstream gene generates a rare transcript (SALF), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product. [provided by RefSeq, Mar 2014]
                Full Name
                    General Transcription Factor IIA Subunit 1 Like
                Function
                    May function as a testis specific transcription factor. Binds DNA in conjunction with GTF2A2 and TBP (the TATA-binding protein) and together with GTF2A2, allows mRNA transcription.
                Biological Process
                    Cognition Source: UniProtKB
Transcription by RNA polymerase II Source: GO_Central
Transcription initiation from RNA polymerase II promoter Source: InterPro
                Transcription by RNA polymerase II Source: GO_Central
Transcription initiation from RNA polymerase II promoter Source: InterPro
Cellular Location
                    Nucleus. Mainly localizes in the annulus and partly in acrosomal cap area of spermatozoa.
                
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                    Anti-GTF2A1L antibodies
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        Target: GTF2A1L
                
                Host: Mouse
                
                Antibody Isotype: IgG1
                
                Specificity: Human
                
                Clone: CBLG1-2092
                
                Application*: E, WB
                
            Target: GTF2A1L
                
                Specificity: Human
                
            Target: GTF2A1L
                
                Specificity: Human
                
            Target: GTF2A1L
                
                Specificity: Human
                
            Target: GTF2A1L
                
                Host: Mouse
                
                Antibody Isotype: IgG2b, κ
                
                Specificity: Human
                
                Clone: 6F5
                
                Application*: WB, E
                
            Target: GTF2A1L
                
                Host: Mouse
                
                Antibody Isotype: IgG2b, κ
                
                Specificity: Human, Rat
                
                Clone: 5B9
                
                Application*: WB, E
                
            Target: GTF2A1L
                
                Host: Mouse
                
                Antibody Isotype: IgG1, κ
                
                Specificity: Human
                
                Clone: 2E3
                
                Application*: WB, E
                
            Target: GTF2A1L
                
                Host: Mouse
                
                Antibody Isotype: IgG2b, κ
                
                Specificity: Human
                
                Clone: CBLG1-2093
                
                Application*: E, WB
                
            Target: GTF2A1L
                
                Host: Mouse
                
                Antibody Isotype: IgG1, κ
                
                Specificity: Human
                
                Clone: 6F5
                
                Application*: E, IP, WB
                
            Target: GTF2A1L
                
                Host: Mouse
                
                Antibody Isotype: IgG2b, κ
                
                Specificity: Human, Rat
                
                Clone: 5B9
                
                Application*: E, WB
                
            Target: GTF2A1L
                
                Host: Mouse
                
                Antibody Isotype: IgG1, κ
                
                Specificity: Human
                
                Clone: 4F5
                
                Application*: E, IP, WB
                
            Target: GTF2A1L
                
                Host: Mouse
                
                Antibody Isotype: IgG2b, κ
                
                Specificity: Human
                
                Clone: 3E4
                
                Application*: E, IF, WB
                
            Target: GTF2A1L
                
                Host: Mouse
                
                Antibody Isotype: IgG1, κ
                
                Specificity: Human
                
                Clone: 2E3
                
                Application*: E, IC, IF, IP, WB
                
            Target: GTF2A1L
                
                Host: Mouse
                
                Antibody Isotype: IgG2b, κ
                
                Specificity: Human
                
                Clone: CBLG1-273
                
                Application*: E, WB
                
            Target: GTF2A1L
                
                Host: Mouse
                
                Antibody Isotype: IgG1, κ
                
                Specificity: Human
                
                Clone: CBFYH-0531
                
                Application*: E, IP, WB
                
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For Research Use Only. Not For Clinical Use.
                    (P): Predicted
* Abbreviations 
- AActivation
 - AGAgonist
 - APApoptosis
 - BBlocking
 - BABioassay
 - BIBioimaging
 - CImmunohistochemistry-Frozen Sections
 - CIChromatin Immunoprecipitation
 - CTCytotoxicity
 - CSCostimulation
 - DDepletion
 - DBDot Blot
 
- EELISA
 - ECELISA(Cap)
 - EDELISA(Det)
 - ESELISpot
 - EMElectron Microscopy
 - FFlow Cytometry
 - FNFunction Assay
 - GSGel Supershift
 - IInhibition
 - IAEnzyme Immunoassay
 - ICImmunocytochemistry
 - IDImmunodiffusion
 - IEImmunoelectrophoresis
 
- IFImmunofluorescence
 - IGImmunochromatography
 - IHImmunohistochemistry
 - IMImmunomicroscopy
 - IOImmunoassay
 - IPImmunoprecipitation
 - ISIntracellular Staining for Flow Cytometry
 - LALuminex Assay
 - LFLateral Flow Immunoassay
 - MMicroarray
 - MCMass Cytometry/CyTOF
 - MDMeDIP
 
- MSElectrophoretic Mobility Shift Assay
 - NNeutralization
 - PImmunohistologyp-Paraffin Sections
 - PAPeptide Array
 - PEPeptide ELISA
 - PLProximity Ligation Assay
 - RRadioimmunoassay
 - SStimulation
 - SESandwich ELISA
 - SHIn situ hybridization
 - TCTissue Culture
 - WBWestern Blot
 
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