GUCY1B1

This gene encodes the beta subunit of the soluble guanylate cyclase (sGC), which catalyzes the conversion of GTP (guanosine triphosphate) to cGMP (cyclic guanosine monophosphate). The encoded protein contains an HNOX domain, which serves as a receptor for ligands such as nitric oxide, oxygen and nitrovasodilator drugs. Alternative splicing results in multiple transcript variants.
Full Name
Guanylate Cyclase 1 Soluble Subunit Beta 1
Function
Mediates responses to nitric oxide (NO) by catalyzing the biosynthesis of the signaling molecule cGMP.
Biological Process
Blood circulation Source: ProtInc
Cellular response to nitric oxide Source: UniProtKB
cGMP biosynthetic process Source: UniProtKB
cGMP-mediated signaling Source: GO_Central
Nitric oxide-cGMP-mediated signaling pathway Source: UniProtKB
Nitric oxide mediated signal transduction Source: ProtInc
Trans-synaptic signaling by nitric oxide, modulating synaptic transmission Source: GO_Central
Cellular Location
Cytoplasm
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Anti-GUCY1B1 antibodies

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Mouse Anti-GUCY1B1 Recombinant Antibody (GC11) (CBMAB-G5780-LY)

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Target: GUCY1B1
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: GC11
Application*: WB
Datasheet SDS

Mouse Anti-GUCY1B1 Recombinant Antibody (G-3) (CBMAB-G5779-LY)

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Target: GUCY1B1
Host: Mouse
Antibody Isotype: IgG
Specificity: Mouse, Rat, Human
Clone: G-3
Application*: WB
Datasheet SDS

Rabbit Anti-GUCY1B1 Recombinant Antibody (CBLG1-3047) (CBMAB-G5778-LY)

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Target: GUCY1B1
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBLG1-3047
Application*: WB
Datasheet SDS

Mouse Anti-GUCY1B1 Recombinant Antibody (10C448) (CBMAB-G5776-LY)

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Target: GUCY1B1
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 10C448
Application*: E, WB
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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