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HELQ

HEL308 is a single-stranded DNA-dependent ATPase and DNA helicase (Marini and Wood, 2002 [PubMed 11751861]).[supplied by OMIM, Mar 2008]

Full Name

Helicase, POLQ Like

Function

Single-stranded DNA-dependent ATPase and 5' to 3' DNA helicase (PubMed:11751861).

Involved in the repair of DNA cross-links and double-strand break (DSB) resistance. Participates in FANCD2-mediated repair. Forms a complex with POLN polymerase that participates in homologous recombination (HR) repair and is essential for cellular protection against DNA cross-links (PubMed:19995904).

Biological Process

Double-strand break repair via homologous recombination Source: UniProtKB
rRNA processing Source: GO_Central

Cellular Location

Nucleus

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Anti-HELQ antibodies

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Rabbit Anti-HELQ Recombinant Antibody (D4K2O) (CBMAB-CP0930-LY)

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Target: HELQ

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human

Clone: D4K2O

Application*: WB

Mouse Anti-HELQ Recombinant Antibody (8C113) (CBMAB-D2086-YC)

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Target: HELQ

Host: Mouse

Antibody Isotype: IgG

Specificity: Human, Mouse, Rat

Clone: 8C113

Application*: WB

Mouse Anti-HELQ Recombinant Antibody (2406C1a) (CBMAB-D2085-YC)

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Target: HELQ

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 2406C1a

Application*: WB, DB

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For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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