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HINT2

Histidine triad proteins, such as HINT2, are nucleotide hydrolases and transferases that act on the alpha-phosphate of ribonucleotides (Brenner, 2002 [PubMed 12119013]).[supplied by OMIM
Full Name
histidine triad nucleotide binding protein 2
Function
Exhibits adenosine 5'-monophosphoramidase activity, hydrolyzing purine nucleotide phosphoramidates with a single phosphate group such as adenosine 5'monophosphoramidate (AMP-NH2) to yield AMP and NH2 (PubMed:16762638, PubMed:31990367).

Hydrolyzes adenosine 5'-O-p-nitrophenylphosphoramidate (AMP-pNA) (PubMed:16762638).

Hydrolyzes fluorogenic purine nucleoside tryptamine phosphoramidates in vitro (PubMed:31990367).

May be involved in steroid biosynthesis (PubMed:18653718).

May play a role in apoptosis (PubMed:16762638).
Biological Process
Apoptotic process Source: UniProtKB-KW
Lipid catabolic process Source: Ensembl
Negative regulation of peptidyl-lysine acetylation Source: Ensembl
Steroid biosynthetic process Source: UniProtKB-KW
Cellular Location
Mitochondrion
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Anti-HINT2 antibodies

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Mouse Anti-HINT2 Recombinant Antibody (4E11) (CBMAB-A3901-LY)

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Target: HINT2
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 4E11
Application*: WB, E
Datasheet SDS

Mouse Anti-HINT2 Recombinant Antibody (CBFYH-1113) (CBMAB-H2066-FY)

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Target: HINT2
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBFYH-1113
Application*: WB
Datasheet SDS

Mouse Anti-HINT2 (AA 18-163) Recombinant Antibody (CBFYH-1112) (CBMAB-H2065-FY)

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Target: HINT2
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBFYH-1112
Application*: WB, F, E, IF
Datasheet SDS

Mouse Anti-HINT2 (AA 60-163) Recombinant Antibody (CBFYH-1111) (CBMAB-H2064-FY)

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Target: HINT2
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBFYH-1111
Application*: E, WB
Datasheet SDS

Mouse Anti-HINT2 Recombinant Antibody (AT5B10) (CBMAB-H2062-FY)

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Target: HINT2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: AT5B10
Application*: E, F, WB
Datasheet SDS
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Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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