HINT2

Histidine triad proteins, such as HINT2, are nucleotide hydrolases and transferases that act on the alpha-phosphate of ribonucleotides (Brenner, 2002 [PubMed 12119013]).[supplied by OMIM

histidine triad nucleotide binding protein 2

Exhibits adenosine 5'-monophosphoramidase activity, hydrolyzing purine nucleotide phosphoramidates with a single phosphate group such as adenosine 5'monophosphoramidate (AMP-NH2) to yield AMP and NH2 (PubMed:16762638, PubMed:31990367).

Hydrolyzes adenosine 5'-O-p-nitrophenylphosphoramidate (AMP-pNA) (PubMed:16762638).

Hydrolyzes fluorogenic purine nucleoside tryptamine phosphoramidates in vitro (PubMed:31990367).

May be involved in steroid biosynthesis (PubMed:18653718).

May play a role in apoptosis (PubMed:16762638).

Apoptotic process Source: UniProtKB-KW
Lipid catabolic process Source: Ensembl
Negative regulation of peptidyl-lysine acetylation Source: Ensembl
Steroid biosynthetic process Source: UniProtKB-KW

Mitochondrion