HPGDS
Prostaglandin-D synthase is a sigma class glutathione-S-transferase family member. The enzyme catalyzes the conversion of PGH2 to PGD2 and plays a role in the production of prostanoids in the immune system and mast cells. The presence of this enzyme can be used to identify the differentiation stage of human megakaryocytes.
Full Name
hematopoietic prostaglandin D synthase
Function
Bifunctional enzyme which catalyzes both the conversion of PGH2 to PGD2, a prostaglandin involved in smooth muscle contraction/relaxation and a potent inhibitor of platelet aggregation, and the conjugation of glutathione with a wide range of aryl halides and organic isothiocyanates. Also exhibits low glutathione-peroxidase activity towards cumene hydroperoxide.
Biological Process
Glutathione metabolic process Source: GO_Central
Locomotory behavior Source: ProtInc
Negative regulation of male germ cell proliferation Source: Ensembl
Prostaglandin biosynthetic process Source: UniProtKB-KW
Prostaglandin metabolic process Source: UniProtKB
Signal transduction Source: ProtInc
Locomotory behavior Source: ProtInc
Negative regulation of male germ cell proliferation Source: Ensembl
Prostaglandin biosynthetic process Source: UniProtKB-KW
Prostaglandin metabolic process Source: UniProtKB
Signal transduction Source: ProtInc
Cellular Location
Cytoplasm
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Anti-HPGDS antibodies
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CompareTarget: HPGDS
Host: Mouse
Antibody Isotype: IgG
Specificity: S. japonicum
Clone: CBLG1-2290
Application*: IH, IP, WB
Target: HPGDS
Host: Mouse
Antibody Isotype: IgG
Specificity: S. japonicum
Clone: CBLG1-2289
Application*: E, IH, WB
Target: HPGDS
Host: Mouse
Antibody Isotype: IgG1
Specificity: S. japonicum
Clone: CBLG1-2288
Application*: E, IP, WB
Target: HPGDS
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: S. japonicum
Clone: CBLG1-2284
Application*: E, IP, WB
Target: HPGDS
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: S. japonicum
Clone: CBLG1-2281
Application*: E, IP, WB
Target: HPGDS
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: S. japonicum
Clone: CBLG1-2275
Application*: E, IP, WB
Target: HPGDS
Host: Mouse
Antibody Isotype: IgG1
Specificity: S. japonicum
Clone: CBLG1-2264
Application*: WB
Target: HPGDS
Host: Mouse
Antibody Isotype: IgG
Specificity: S. japonicum
Clone: CBLG1-2261
Application*: IH, IP, WB
Target: HPGDS
Host: Mouse
Antibody Isotype: IgG
Specificity: Mouse
Clone: CBLG1-2260
Application*: E, IH, WB
Target: HPGDS
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: CBLG1-2256
Application*: E, IP, WB
Target: HPGDS
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: S. japonicum
Clone: CBLG1-2245
Application*: E, IH, IP, WB
Target: HPGDS
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: S. japonicum
Clone: CBLG1-2244
Application*: E, IP, WB
Target: HPGDS
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Rat, Monkey
Clone: L70B11
Application*: WB
Target: HPGDS
Host: Mouse
Antibody Isotype: IgG1
Specificity: S. japonicum
Clone: BDI340
Application*: E, IP, WB
Target: HPGDS
Host: Rat
Antibody Isotype: IgG2a
Specificity: S. japonicum
Clone: 6G9
Application*: WB
Target: HPGDS
Host: Mouse
Antibody Isotype: IgG1
Specificity: S. japonicum
Clone: 6E5
Application*: WB
Target: HPGDS
Host: Mouse
Antibody Isotype: IgG1
Specificity: S. japonicum
Clone: 6D42E1
Application*: E, IP, WB
Target: HPGDS
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse, Ferret
Clone: 3G10
Application*: WB
Target: HPGDS
Host: Mouse
Antibody Isotype: IgG1
Specificity: S. japonicum
Clone: 1B3
Application*: IF, IP, WB
Target: HPGDS
Host: Mouse
Antibody Isotype: IgG1
Specificity: S. japonicum
Clone: 17B6
Application*: WB
Target: HPGDS
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 15TF2‐1D10
Application*: E, WB
Target: HPGDS
Host: Mouse
Antibody Isotype: IgG
Specificity: Mouse, Human
Clone: CBLG1-2065
Application*: E, IH, IP, WB
Target: HPGDS
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: S. japonicum
Clone: CBLG1-308
Application*: E, IP, WB
Target: HPGDS
Host: Mouse
Antibody Isotype: IgG1
Specificity: S. japonicum
Clone: CBLG1-306
Application*: WB
Target: HPGDS
Host: Mouse
Antibody Isotype: IgG1
Specificity: S. japonicum
Clone: CBLG1-303
Application*: E, WB
Target: HPGDS
Host: Alpaca
Antibody Isotype: VHH
Specificity: S. japonicum
Clone: CBLG1-3060
Application*: IP
Target: HPGDS
Host: Mouse
Antibody Isotype: IgG1
Specificity: S. japonicum
Clone: CBLG1-299
Application*: E, WB
Target: HPGDS
Host: Mouse
Antibody Isotype: IgG1
Specificity: S. japonicum
Clone: vpg66
Application*: E, WB
Target: HPGDS
Host: Mouse
Antibody Isotype: IgG1
Specificity: S. japonicum
Clone: 3H2162
Application*: E, WB
Target: HPGDS
Host: Mouse
Antibody Isotype: IgG1
Specificity: S. japonicum
Clone: 2H3-D10
Application*: WB
Target: HPGDS
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: S. japonicum
Clone: 21CT54.13.1/21CT54.13.7
Application*: E, WB
Target: HPGDS
Host: Rat
Antibody Isotype: IgG
Specificity: Mouse
Clone: CBFYH-1896
Application*: P, WB
Target: HPGDS
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYH-1895
Application*: WB
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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