HSD17B11

Short-chain alcohol dehydrogenases, such as HSD17B11, metabolize secondary alcohols and ketones (Brereton et al., 2001 [PubMed 11165019]).[supplied by OMIM, Jun 2009]

Hydroxysteroid 17-Beta Dehydrogenase 11

Can convert androstan-3-alpha,17-beta-diol (3-alpha-diol) to androsterone in vitro, suggesting that it may participate in androgen metabolism during steroidogenesis. May act by metabolizing compounds that stimulate steroid synthesis and/or by generating metabolites that inhibit it. Has no activity toward DHEA (dehydroepiandrosterone), or A-dione (4-androste-3,17-dione), and only a slight activity toward testosterone to A-dione. Tumor-associated antigen in cutaneous T-cell lymphoma.

Androgen catabolic process Source: HGNC-UCL
Estrogen biosynthetic process Source: Reactome

Endoplasmic reticulum; Lipid droplet. Redistributed from the endoplasmic reticulum to lipids droplets in the cell upon induction of lipids droplet formation.