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IGFBP4

This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein binds both insulin-like growth factors (IGFs) I and II and circulates in the plasma in both glycosylated and non-glycosylated forms. Binding of this protein prolongs the half-life of the IGFs and alters their interaction with cell surface receptors. [provided by RefSeq, Jul 2008]
Full Name
Insulin Like Growth Factor Binding Protein 4
Function
IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.
Biological Process
Inflammatory response Source: Ensembl
Negative regulation of canonical Wnt signaling pathway Source: ParkinsonsUK-UCL
Positive regulation of insulin-like growth factor receptor signaling pathway Source: Ensembl
Positive regulation of MAPK cascade Source: Ensembl
Regulation of cell growth Source: Ensembl
Regulation of glucose metabolic process Source: Ensembl
Regulation of insulin-like growth factor receptor signaling pathway Source: GO_Central
Signal transduction Source: ProtInc
Type B pancreatic cell proliferation Source: Ensembl
Cellular Location
Secreted

Anti-IGFBP4 antibodies

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Mouse Anti-IGFBP4 Recombinant Antibody (1.A.17) (CBMAB-I0143-YY)

Datasheet SDS
Target: IGFBP4
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 1.A.17
Application*: WB, E, P

Mouse Anti-IGFBP4 Recombinant Antibody (CBYY-I0060) (CBMAB-I0147-YY)

Datasheet SDS
Target: IGFBP4
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human, Mouse
Clone: CBYY-I0060
Application*: E, Sandwich E

Mouse Anti-IGFBP4 Recombinant Antibody (CBYY-I0721) (CBMAB-I1609-YY)

Datasheet SDS
Target: IGFBP4
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBYY-I0721
Application*: WB

Mouse Anti-IGFBP4 Recombinant Antibody (CBYY-I0769) (CBMAB-I1710-YY)

Datasheet SDS
Target: IGFBP4
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-I0769
Application*: WB, N, EC

Mouse Anti-IGFBP4 Recombinant Antibody (CBYY-I1043) (CBMAB-I2211-YY)

Datasheet SDS
Target: IGFBP4
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYY-I1043
Application*: E

Mouse Anti-IGFBP4 Recombinant Antibody (IBP144) (CBMAB-A4466-YC)

Datasheet SDS
Target: IGFBP4
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: IBP144
Application*: E

Mouse Anti-IGFBP4 Recombinant Antibody (IBP163) (CBMAB-A4468-YC)

Datasheet SDS
Target: IGFBP4
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: IBP163
Application*: E

Mouse Anti-IGFBP4 Recombinant Antibody (CBYY-I0057) (CBMAB-I0144-YY)

Datasheet SDS
Target: IGFBP4
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human, Mouse
Clone: CBYY-I0057
Application*: E, Sandwich E

Mouse Anti-IGFBP4 Recombinant Antibody (CBYY-I0058) (CBMAB-I0145-YY)

Datasheet SDS
Target: IGFBP4
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse
Clone: CBYY-I0058
Application*: E, Sandwich E

Mouse Anti-IGFBP4 Recombinant Antibody (CBYY-I0061) (CBMAB-I0148-YY)

Datasheet SDS
Target: IGFBP4
Host: Mouse
Antibody Isotype: IgG3
Specificity: Human, Mouse
Clone: CBYY-I0061
Application*: E, Sandwich E

Mouse Anti-IGFBP4 Recombinant Antibody (B1532M) (CBMAB-I1944-YY)

Datasheet SDS
Target: IGFBP4
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: B1532M
Application*: E

Mouse Anti-IGFBP4 Recombinant Antibody (CBYY-I1297) (CBMAB-I2466-YY)

Datasheet SDS
Target: IGFBP4
Host: Mouse
Antibody Isotype: IgG2
Specificity: Human
Clone: CBYY-I1297
Application*: N, WB

Mouse Anti-IGFBP4 Recombinant Antibody (IBP185) (CBMAB-A4470-YC)

Datasheet SDS
Target: IGFBP4
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: IBP185
Application*: E

Mouse Anti-IGFBP4 Recombinant Antibody (IBP3) (CBMAB-A4471-YC)

Datasheet SDS
Target: IGFBP4
Host: Mouse
Antibody Isotype: IgG3
Specificity: Human
Clone: IBP3
Application*: E

Mouse Anti-IGFBP4 Recombinant Antibody (CBYC-A980) (CBMAB-A4472-YC)

Datasheet SDS
Target: IGFBP4
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYC-A980
Application*: E, WB

Mouse Anti-IGFBP4 Recombinant Antibody (A436) (CBMAB-AP3829LY)

Datasheet SDS
Target: IGFBP4
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human, Rat
Clone: A436
Application*: ICC, IHC, IP, WB

Mouse Anti-IGFBP4 Recombinant Antibody (A437) (CBMAB-AP3830LY)

Datasheet SDS
Target: IGFBP4
Host: Mouse
Antibody Isotype: IgG
Specificity: Human, Rat
Clone: A437
Application*: ICC, IHC, IP, WB

Mouse Anti-IGFBP4 Recombinant Antibody (A438) (CBMAB-AP3831LY)

Datasheet SDS
Target: IGFBP4
Host: Mouse
Antibody Isotype: IgG
Specificity: Human, Rat
Clone: A438
Application*: ICC, IHC, IP, WB
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
IFImmunofluorescence
IHImmunohistochemistry
IPImmunoprecipitation
WBWestern Blot
EELISA
MMicroarray
CIChromatin Immunoprecipitation
FFlow Cytometry
FNFunction Assay
IDImmunodiffusion
RRadioimmunoassay
TCTissue Culture
GSGel Supershift
NNeutralization
BBlocking
AActivation
IInhibition
DDepletion
ESELISpot
DBDot Blot
MCMass Cytometry/CyTOF
CTCytotoxicity
SStimulation
AGAgonist
APApoptosis
IMImmunomicroscopy
BABioassay
CSCostimulation
EMElectron Microscopy
IEImmunoelectrophoresis
PAPeptide Array
ICImmunocytochemistry
PEPeptide ELISA
MDMeDIP
SHIn situ hybridization
IAEnzyme Immunoassay
SEsandwich ELISA
PLProximity Ligation Assay
ECELISA(Cap)
EDELISA(Det)
BIBioimaging
IOImmunoassay
LFLateral Flow Immunoassay
LALuminex Assay
CImmunohistochemistry-Frozen Sections
PImmunohistologyp-Paraffin Sections
ISIntracellular Staining for Flow Cytometry
MSElectrophoretic Mobility Shift Assay
RIRNA Binding Protein Immunoprecipitation (RIP)
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