IL17D

The protein encoded by this gene is a cytokine that shares the sequence similarity with IL17. The treatment of endothelial cells with this cytokine has been shown to stimulate the production of other cytokines including IL6, IL8 and CSF2/ GM-CSF. The increased expression of IL8 induced by this cytokine was found to be NF-kappa B-dependent. [provided by RefSeq, Jul 2008]
Full Name
Interleukin 17D
Function
Induces expression of IL6, CXCL8/IL8, and CSF2/GM-CSF from endothelial cells.
Biological Process
Inflammatory response Source: UniProtKB
Negative regulation of hemopoiesis Source: UniProtKB
Positive regulation of cytokine production involved in inflammatory response Source: UniProtKB
Positive regulation of granulocyte macrophage colony-stimulating factor production Source: UniProtKB
Positive regulation of interleukin-6 production Source: UniProtKB
Positive regulation of interleukin-8 production Source: UniProtKB
Cellular Location
Secreted
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Anti-IL17D antibodies

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Target: IL17D
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: A481
Application*: ELISA, WB
Target: IL17D
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CF223
Application*: ELISA, WB
Target: IL17D
Host: Rat
Antibody Isotype: IgG2a
Specificity: Mouse
Clone: 8H142
Application*: E, F, WB
Target: IL17D
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 246018
Application*: E, F, P, WB, MC, IS
Target: IL17D
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBYY-I0148
Application*: WB, BL, E
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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