IL17D

The protein encoded by this gene is a cytokine that shares the sequence similarity with IL17. The treatment of endothelial cells with this cytokine has been shown to stimulate the production of other cytokines including IL6, IL8 and CSF2/ GM-CSF. The increased expression of IL8 induced by this cytokine was found to be NF-kappa B-dependent. [provided by RefSeq, Jul 2008]

Interleukin 17D

Induces expression of IL6, CXCL8/IL8, and CSF2/GM-CSF from endothelial cells.

Inflammatory response Source: UniProtKB
Negative regulation of hemopoiesis Source: UniProtKB
Positive regulation of cytokine production involved in inflammatory response Source: UniProtKB
Positive regulation of granulocyte macrophage colony-stimulating factor production Source: UniProtKB
Positive regulation of interleukin-6 production Source: UniProtKB
Positive regulation of interleukin-8 production Source: UniProtKB

Secreted