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Rat Anti-IL17D Recombinant Antibody (8H142) (CBMAB-I1778-YY)

This product is Rat antibody that recognizes IL17D. The antibody 8H142 can be used for immunoassay techniques such as: ELISA, FC, WB
See all IL17D antibodies

Summary

Host Animal
Rat
Specificity
Mouse
Clone
8H142
Antibody Isotype
IgG2a
Application
ELISA, FC, WB

Basic Information

Specificity
Mouse
Antibody Isotype
IgG2a
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Preservative
0.1% sodium azide
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
Interleukin 17D
Introduction
The protein encoded by this gene is a cytokine that shares the sequence similarity with IL17. The treatment of endothelial cells with this cytokine has been shown to stimulate the production of other cytokines including IL6, IL8 and CSF2/ GM-CSF. The increased expression of IL8 induced by this cytokine was found to be NF-kappa B-dependent.
Entrez Gene ID
239114
UniProt ID
Q8K4C4
Alternative Names
Interleukin 17D
Function
Induces expression of IL6, CXCL8/IL8, and CSF2/GM-CSF from endothelial cells.
Biological Process
Inflammatory response Source: UniProtKB
Negative regulation of hemopoiesis Source: UniProtKB
Positive regulation of cytokine production involved in inflammatory response Source: UniProtKB
Positive regulation of granulocyte macrophage colony-stimulating factor production Source: UniProtKB
Positive regulation of interleukin-6 production Source: UniProtKB
Positive regulation of interleukin-8 production Source: UniProtKB
Cellular Location
Secreted
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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