IL20RB
IL20RB and IL20RA (MIM 605620) form a heterodimeric receptor for interleukin-20.
Full Name
interleukin 20 receptor subunit beta
Function
The IL20RA/IL20RB dimer is a receptor for IL19, IL20 and IL24. The IL22RA1/IL20RB dimer is a receptor for IL20 and IL24.
Biological Process
Cytokine-mediated signaling pathwayManual Assertion Based On ExperimentIBA:GO_Central
Homeostasis of number of cells within a tissueIEA:Ensembl
Immune response-inhibiting signal transductionIEA:Ensembl
Inflammatory response to antigenic stimulusIEA:Ensembl
Negative regulation of interferon-gamma productionIEA:Ensembl
Negative regulation of interleukin-2 productionIEA:Ensembl
Negative regulation of T cell proliferationIEA:Ensembl
Negative regulation of type IV hypersensitivityIEA:Ensembl
Positive regulation of interleukin-10 productionIEA:Ensembl
Positive regulation of interleukin-4 productionIEA:Ensembl
Homeostasis of number of cells within a tissueIEA:Ensembl
Immune response-inhibiting signal transductionIEA:Ensembl
Inflammatory response to antigenic stimulusIEA:Ensembl
Negative regulation of interferon-gamma productionIEA:Ensembl
Negative regulation of interleukin-2 productionIEA:Ensembl
Negative regulation of T cell proliferationIEA:Ensembl
Negative regulation of type IV hypersensitivityIEA:Ensembl
Positive regulation of interleukin-10 productionIEA:Ensembl
Positive regulation of interleukin-4 productionIEA:Ensembl
Cellular Location
Membrane
Topology
Extracellular: 30-233
Helical: 234-254
Cytoplasmic: 255-311
Helical: 234-254
Cytoplasmic: 255-311
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Anti-IL20RB antibodies
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Target: IL20RB
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: A533
Application*: ELISA, WB
Target: IL20RB
Host: Rat
Antibody Isotype: IgG2a, κ
Specificity: Human, Mouse
Clone: 20RNTC
Application*: F, IC, IF, WB
Target: IL20RB
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 1-225
Tag: His Tag
Target: IL20RB
Expressed Host: Baculovirus-Insect Cells
Sequence: Amino Acid: 1-230
Tag: His Tag
Target: IL20RB
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 1-227
Tag: His Tag
Target: IL20RB
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 1-227
Tag: hFc Tag
Target: IL20RB
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 30-230
Tag: His Tag
Target: IL20RB
Expressed Host: HEK293 Cells
Sequence: Amino Acid: 30-230
Tag: hFc Tag
Target: IL20RB
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Mouse
Clone: EG1641
Application*: WB: 1:500~1:1000 ELISA: 1:20000
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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
- AActivation
- AGAgonist
- APApoptosis
- BBlocking
- BABioassay
- BIBioimaging
- CImmunohistochemistry-Frozen Sections
- CIChromatin Immunoprecipitation
- CTCytotoxicity
- CSCostimulation
- DDepletion
- DBDot Blot
- EELISA
- ECELISA(Cap)
- EDELISA(Det)
- ESELISpot
- EMElectron Microscopy
- FFlow Cytometry
- FNFunction Assay
- GSGel Supershift
- IInhibition
- IAEnzyme Immunoassay
- ICImmunocytochemistry
- IDImmunodiffusion
- IEImmunoelectrophoresis
- IFImmunofluorescence
- IGImmunochromatography
- IHImmunohistochemistry
- IMImmunomicroscopy
- IOImmunoassay
- IPImmunoprecipitation
- ISIntracellular Staining for Flow Cytometry
- LALuminex Assay
- LFLateral Flow Immunoassay
- MMicroarray
- MCMass Cytometry/CyTOF
- MDMeDIP
- MSElectrophoretic Mobility Shift Assay
- NNeutralization
- PImmunohistologyp-Paraffin Sections
- PAPeptide Array
- PEPeptide ELISA
- PLProximity Ligation Assay
- RRadioimmunoassay
- SStimulation
- SESandwich ELISA
- SHIn situ hybridization
- TCTissue Culture
- WBWestern Blot
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