Cynomolgus Recombinant IL20RB protein, hFc Tag (V2LY-0526-LY1565)

Name: Cynomolgus Recombinant IL20RB protein, hFc Tag
SKU: V2LY-0526-LY1565
Rating: 5 (1 reviews)

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Datasheet

SDS

Request for COA

Datasheet Target References Q & As Review & reward Protocols Associated Products

Basic Information

Expressed Host

HEK293 Cells

Protein Species

Cynomolgus

Tag

hFc Tag

Protein Construction

This product is Cynomolgus Recombinant IL20RB protein, hFc Tag consist of Amino Acid: 30-230 and predicts a molecular mass of 49.2 kDa.

Molecule Mass

49.2 kDa

Sequence

Amino Acid: 30-230

Species

Cynomolgus

Formulations & Storage [For reference only, actual COA shall prevail!]

Purity

>90% as determined by SDS-PAGE.

Endotoxin

Please contact us for more information.

Format

Lyophilized

Reconstitution

Allow the vial and reconstitution buffer to equilibrate to room temperature. Briefly centrifuge or tap down the vial to ensure that all lyophilized powder is collected at the bottom of the vial. For the reconstitution of this product, we recommend adding PBS or sterile water to achieve a final antibody concentration of 1 mg/mL. Allow the vial to reconstitute for 10-15 minutes at room temperature with gentle agitation. Avoid vigorous shaking that can cause foaming and antibody denaturation. Aliquot into volumes based on your experiment and store liquid protein at -20°C or -80°C for long time.

Buffer

Lyophilized from sterile Tris, NaCl, Arginine, Glycerol, Trehalose

Preservative

None

Storage

Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.

More Infomation

Target

Full Name

interleukin 20 receptor subunit beta

Function

The IL20RA/IL20RB dimer is a receptor for IL19, IL20 and IL24. The IL22RA1/IL20RB dimer is a receptor for IL20 and IL24.

Biological Process

Cytokine-mediated signaling pathwayManual Assertion Based On ExperimentIBA:GO_Central
Homeostasis of number of cells within a tissueIEA:Ensembl
Immune response-inhibiting signal transductionIEA:Ensembl
Inflammatory response to antigenic stimulusIEA:Ensembl
Negative regulation of interferon-gamma productionIEA:Ensembl
Negative regulation of interleukin-2 productionIEA:Ensembl
Negative regulation of T cell proliferationIEA:Ensembl
Negative regulation of type IV hypersensitivityIEA:Ensembl
Positive regulation of interleukin-10 productionIEA:Ensembl
Positive regulation of interleukin-4 productionIEA:Ensembl

Cellular Location

Membrane

Topology

Extracellular: 30-233
Helical: 234-254
Cytoplasmic: 255-311

Guo, H., Jiang, S., Sun, H., Shi, B., Li, Y., Zhou, N., ... & Guo, H. (2022). Identification of IL20RB as a novel prognostic and therapeutic biomarker in clear cell renal cell carcinoma. Disease Markers, 2022.

Zhang, H., Liu, Y., Wang, B., & Wang, C. (2022). Interleukin 20 receptor subunit beta (IL20RB) predicts poor prognosis and regulates immune cell infiltration in clear cell renal cell carcinoma. BMC Genomic Data, 23(1), 1-14.

Kong, L., Jiang, D., He, C., Xia, J., Wei, H., Zhou, L., & Peng, H. (2020). TgROP18 targets IL20RB for host-defense-related-STAT3 activation during Toxoplasma gondii infection. Parasites & Vectors, 13(1), 1-14.

Kong, L., Jiang, D., He, C., Xia, J., We, H., Zhou, L., & Peng, H. J. (2020). TgROP18 Targets IL20RB for Host-Defense-Related-STAT3 Activation During T. gondii Infection.

Cui, X. F., Cui, X. G., & Leng, N. (2019). Overexpression of interleukin-20 receptor subunit beta (IL20RB) correlates with cell proliferation, invasion and migration enhancement and poor prognosis in papillary renal cell carcinoma. Journal of Toxicologic Pathology, 32(4), 245-251.

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Please try the standard protocols which include: protocols, troubleshooting and guide.

Enzyme-linked Immunosorbent Assay (ELISA)
Flow Cytometry
Immunofluorescence (IF)
Immunohistochemistry (IHC)
Immunoprecipitation (IP)
Western Blot (WB)
Enzyme Linked Immunospot (ELISpot)
Proteogenomic
Other Protocols

Alternative Versions

Cynomolgus Recombinant IL20RB protein, His Tag (CAT#: V2LY-0526-LY1566)

Rat Recombinant IL20RB protein, hFc Tag (CAT#: V2LY-0526-LY9456)

Rat Recombinant IL20RB protein, His Tag (CAT#: V2LY-0526-LY9457)

Human Recombinant IL20RB protein, ECD, His Tag (CAT#: V2LY-0526-LY4833)

Mouse Recombinant IL20RB protein, ECD, His Tag (CAT#: V2LY-0526-LY8514)

Related Products

Mouse Anti-IL20RB Recombinant Antibody (A533) (CAT#: CBMAB-AP10889LY)

Rat Recombinant IL20RB protein, hFc Tag (CAT#: V2LY-0526-LY9456)

Rabbit Anti-IL20RB Recombinant Antibody (EG1641) (CAT#: CBMAB-EN1964-LY)

Cynomolgus Recombinant IL20RB protein, His Tag (CAT#: V2LY-0526-LY1566)

Mouse Recombinant IL20RB protein, ECD, His Tag (CAT#: V2LY-0526-LY8514)

Rat Recombinant IL20RB protein, His Tag (CAT#: V2LY-0526-LY9457)

Human Recombinant IL20RB protein, ECD, His Tag (CAT#: V2LY-0526-LY4833)

Rat Anti-IL20RB Recombinant Antibody (20RNTC) (CAT#: CBMAB-I0489-YY)

Isotype control

For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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