KDM4B

Histone demethylase that specifically demethylates Lys-9 of histone H3, thereby playing a role in histone code. Does not demethylate histone H3 Lys-4, H3 Lys-27, H3 Lys-36 nor H4 Lys-20. Only able to demethylate trimethylated H3 Lys-9, with a weaker activity than KDM4A, KDM4C and KDM4D. Demethylation of Lys residue generates formaldehyde and succinate.
Full Name
lysine demethylase 4B
Function
Histone demethylase that specifically demethylates 'Lys-9' of histone H3, thereby playing a role in histone code. Does not demethylate histone H3 'Lys-4', H3 'Lys-27', H3 'Lys-36' nor H4 'Lys-20'. Only able to demethylate trimethylated H3 'Lys-9', with a weaker activity than KDM4A, KDM4C and KDM4D. Demethylation of Lys residue generates formaldehyde and succinate.
Biological Process
Chromatin remodelingManual Assertion Based On ExperimentIBA:GO_Central
Histone H3-K36 demethylationManual Assertion Based On ExperimentIDA:UniProtKB
Histone H3-K9 demethylationManual Assertion Based On ExperimentIDA:UniProtKB
Cellular Location
Nucleus
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Anti-KDM4B antibodies

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Rabbit Anti-KDM4B Recombinant Antibody (D7E6) (CBMAB-CP1269-LY)

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Target: KDM4B
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human, Monkey
Clone: D7E6
Application*: WB, IP, IF (IC)
Datasheet SDS

Mouse Anti-KDM4B Recombinant Antibody (F-12) (CBMAB-0352-WJ)

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Target: KDM4B
Host: Mouse
Specificity: Mouse
Clone: F-12
Application*: WB, IP, IF, E
Datasheet SDS

Mouse Anti-KDM4B Recombinant Antibody (CBT3684) (V2LY-0625-LY710)

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Target: KDM4B
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human, Mouse
Clone: CBT3684
Application*: F
Datasheet SDS

Rabbit Anti-KDM4B Recombinant Antibody (EG1713) (CBMAB-EN2051-LY)

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Target: KDM4B
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: EG1713
Application*: IHC: 1:50~1:100 ELISA: 1:1000
Datasheet SDS

Rabbit Anti-KDM4B Recombinant Antibody (CBLY1-067) (CBMAB-K0691-LY)

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Target: KDM4B
Host: Rabbit
Antibody Isotype: IgG
Specificity: Mouse, Rat, Human
Clone: CBLY1-067
Application*: WB, P, IC/IF
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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