KIF17

Transports vesicles containing N-methyl-D-aspartate (NMDA) receptor 2B along microtubules.

Full Name

kinesin family member 17

Function

Dendrite-specific motor protein which, in association with the Apba1-containing complex (LIN-10-LIN-2-LIN-7 complex), transports vesicles containing N-methyl-D-aspartate (NMDA) receptor subunit NR2B along microtubules.

Biological Process

Anterograde dendritic transport of neurotransmitter receptor complexManual Assertion Based On ExperimentIBA:GO_Central
Cell projection organizationManual Assertion Based On ExperimentIBA:GO_Central
Microtubule-based movementManual Assertion Based On ExperimentIBA:GO_Central
Protein transportIEA:UniProtKB-KW
Vesicle-mediated transportIEA:Ensembl

Cellular Location

Cytoplasm, cytoskeleton; Cell projection, cilium; Cell projection, dendrite. Localizes to dendrites of pyramidal neurons (By similarity).
Does not localize to the axons or nuclei in cerebral cortex, hippocampus or olfactory bulb (By similarity).
Co-localizes with NR2B-containing vesicles along microtubules (By similarity).

Anti-KIF17 antibodies

Mouse Anti-KIF17 Recombinant Antibody (7C6) (CBMAB-K0847-LY)

Datasheet

SDS

Target: KIF17

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: 7C6

Application*: E, WB

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)