KIF17

Transports vesicles containing N-methyl-D-aspartate (NMDA) receptor 2B along microtubules.

Full Name

kinesin family member 17

Function

Dendrite-specific motor protein which, in association with the Apba1-containing complex (LIN-10-LIN-2-LIN-7 complex), transports vesicles containing N-methyl-D-aspartate (NMDA) receptor subunit NR2B along microtubules.

Biological Process

Anterograde dendritic transport of neurotransmitter receptor complexManual Assertion Based On ExperimentIBA:GO_Central
Cell projection organizationManual Assertion Based On ExperimentIBA:GO_Central
Microtubule-based movementManual Assertion Based On ExperimentIBA:GO_Central
Protein transportIEA:UniProtKB-KW
Vesicle-mediated transportIEA:Ensembl

Cellular Location

Cytoplasm, cytoskeleton; Cell projection, cilium; Cell projection, dendrite. Localizes to dendrites of pyramidal neurons (By similarity).
Does not localize to the axons or nuclei in cerebral cortex, hippocampus or olfactory bulb (By similarity).
Co-localizes with NR2B-containing vesicles along microtubules (By similarity).