LBX1

This gene and the orthologous mouse gene were found by their homology to the Drosophila lady bird early and late homeobox genes. In the mouse, this gene is a key regulator of muscle precursor cell migration and is required for the acquisition of dorsal identities of forelimb muscles. [provided by RefSeq]

LBX1

Transcription factor required for the development of GABAergic interneurons in the dorsal horn of the spinal cord and migration and further development of hypaxial muscle precursor cells for limb muscles, diaphragm and hypoglossal cord.

Anatomical structure morphogenesisManual Assertion Based On ExperimentTAS:ProtInc
Heart loopingIEA:Ensembl
Muscle organ developmentIEA:UniProtKB-KW
Negative regulation of cell population proliferationIEA:Ensembl
Negative regulation of neuron differentiationIEA:Ensembl
Neuron fate determinationIEA:Ensembl
Regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIBA:GO_Central
Spinal cord motor neuron differentiationIEA:Ensembl

Nucleus