LHX2

This gene encodes a protein belonging to a large protein family, members of which carry the LIM domain, a unique cysteine-rich zinc-binding domain. The encoded protein may function as a transcriptional regulator. The protein can recapitulate or rescue phenotypes in Drosophila caused by a related protein, suggesting conservation of function during evolution. [provided by RefSeq]

LHX2

Acts as a transcriptional activator. Stimulates the promoter of the alpha-glycoprotein gene. Transcriptional regulatory protein involved in the control of cell differentiation in developing lymphoid and neural cell types (By similarity).

Axon extensionIEA:Ensembl
Axon guidanceIEA:Ensembl
Cerebral cortex developmentIEA:Ensembl
Dorsal/ventral pattern formationIEA:Ensembl
Hair follicle developmentIEA:Ensembl
Maintenance of epithelial cell apical/basal polarityIEA:Ensembl
Mesoderm developmentIEA:Ensembl
Negative regulation of gene expression, epigeneticIEA:Ensembl
Negative regulation of neurogenesisIEA:Ensembl
Negative regulation of transcription regulatory region DNA bindingIEA:Ensembl
Neural tube closureIEA:Ensembl
Neuron differentiationManual Assertion Based On ExperimentIBA:GO_Central
Olfactory bulb developmentIEA:Ensembl
Positive regulation of neural precursor cell proliferationIEA:Ensembl
Positive regulation of transcription, DNA-templatedISS:UniProtKB
Regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIBA:GO_Central
Retina development in camera-type eyeIEA:Ensembl
Telencephalon regionalizationIEA:Ensembl

Nucleus