LHX2

This gene encodes a protein belonging to a large protein family, members of which carry the LIM domain, a unique cysteine-rich zinc-binding domain. The encoded protein may function as a transcriptional regulator. The protein can recapitulate or rescue phenotypes in Drosophila caused by a related protein, suggesting conservation of function during evolution. [provided by RefSeq]
Full Name
LHX2
Function
Acts as a transcriptional activator. Stimulates the promoter of the alpha-glycoprotein gene. Transcriptional regulatory protein involved in the control of cell differentiation in developing lymphoid and neural cell types (By similarity).
Biological Process
Axon extensionIEA:Ensembl
Axon guidanceIEA:Ensembl
Cerebral cortex developmentIEA:Ensembl
Dorsal/ventral pattern formationIEA:Ensembl
Hair follicle developmentIEA:Ensembl
Maintenance of epithelial cell apical/basal polarityIEA:Ensembl
Mesoderm developmentIEA:Ensembl
Negative regulation of gene expression, epigeneticIEA:Ensembl
Negative regulation of neurogenesisIEA:Ensembl
Negative regulation of transcription regulatory region DNA bindingIEA:Ensembl
Neural tube closureIEA:Ensembl
Neuron differentiationManual Assertion Based On ExperimentIBA:GO_Central
Olfactory bulb developmentIEA:Ensembl
Positive regulation of neural precursor cell proliferationIEA:Ensembl
Positive regulation of transcription, DNA-templatedISS:UniProtKB
Regulation of transcription by RNA polymerase IIManual Assertion Based On ExperimentIBA:GO_Central
Retina development in camera-type eyeIEA:Ensembl
Telencephalon regionalizationIEA:Ensembl
Cellular Location
Nucleus
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Anti-LHX2 antibodies

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Mouse Anti-LHX2 Recombinant Antibody (CBT844) (V2LY-0625-LY3236)

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Target: LHX2
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBT844
Application*: WB, IF, IC, E
Datasheet SDS

Mouse Anti-LHX2 Recombinant Antibody (CBT4434) (V2LY-0625-LY2539)

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Target: LHX2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT4434
Application*: IC
Datasheet SDS

Mouse Anti-LHX2 Recombinant Antibody (CBYCL-295) (CBMAB-L0196-YC)

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Target: LHX2
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBYCL-295
Application*: E, WB
Datasheet SDS

Mouse Anti-LHX2 Recombinant Antibody (CBYJL-1618) (CBMAB-L1468-YJ)

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Target: LHX2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBYJL-1618
Application*: WB, IH, E
Datasheet SDS

Mouse Anti-LHX2 Recombinant Antibody (LHX2A12G1) (CBMAB-L1467-YJ)

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Target: LHX2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: LHX2A12G1
Application*: DB, IC
Datasheet SDS

Mouse Anti-LHX2 Recombinant Antibody (CBYJL-1616) (CBMAB-L1465-YJ)

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Target: LHX2
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBYJL-1616
Application*: WB
Datasheet SDS

Mouse Anti-LHX2 Recombinant Antibody (6G2) (CBMAB-L1464-YJ)

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Target: LHX2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 6G2
Application*: WB, E, IC, IF
Datasheet SDS

Mouse Anti-LHX2 Recombinant Antibody (285CT11.1.1) (CBMAB-L1463-YJ)

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Target: LHX2
Host: Mouse
Antibody Isotype: IgM, κ
Specificity: Human
Clone: 285CT11.1.1
Application*: E, WB
Datasheet SDS

Mouse Anti-LHX2 Recombinant Antibody (CBYJL-1615) (CBMAB-L1462-YJ)

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Target: LHX2
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBYJL-1615
Application*: E, WB
Datasheet SDS

Mouse Anti-LHX2 Recombinant Antibody (13B474) (CBMAB-L1461-YJ)

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Target: LHX2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 13B474
Application*: E, WB
Datasheet SDS

Mouse Anti-LHX2 Antibody (3B11) (CBMAB-0622-YC)

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Target: LHX2
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 3B11
Application*: IP, M
Datasheet SDS

Mouse Anti-LHX2 Antibody (2E3) (CBMAB-0620-YC)

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Target: LHX2
Host: Mouse
Antibody Isotype: IgG2c
Specificity: Human
Clone: 2E3
Application*: IP, WB, M
Datasheet SDS

Mouse Anti-LHX2 Antibody (2D12) (CBMAB-0619-YC)

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Target: LHX2
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 2D12
Application*: IP, M
Datasheet SDS

Mouse Anti-LHX2 Antibody (1C11) (CBMAB-0617-YC)

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Target: LHX2
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 1C11
Application*: IP, M
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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