LILRB5

LILRB5 is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13. 4. LILRB5 belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). Several other LIR subfamily B receptors are expressed on immune cells where they bind to MHC class I molecules on antigen-presenting cells and inhibit stimulation of an immune response. Multiple transcript variants encoding different isoforms have been found for this gene. Among its related pathways are Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell and Osteoclast differentiation.
Full Name
Leukocyte Immunoglobulin Like Receptor B5
Function
May act as receptor for class I MHC antigens.
Biological Process
Adaptive immune responseIEA:UniProtKB-KW
Cell surface receptor signaling pathwayManual Assertion Based On ExperimentTAS:ProtInc
Cytokine-mediated signaling pathwayManual Assertion Based On ExperimentIBA:GO_Central
Defense responseManual Assertion Based On ExperimentTAS:ProtInc
Cellular Location
Membrane
Topology
Extracellular: 24-458
Helical: 459-479
Cytoplasmic: 480-590
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Anti-LILRB5 antibodies

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Mouse Anti-LILRB5 Recombinant Antibody (CBT4138) (V2LY-0625-LY1113)

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Target: LILRB5
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBT4138
Application*: F
Datasheet SDS

Mouse Anti-LILRB5 Recombinant Antibody (CBYCL-330) (CBMAB-L0231-YC)

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Target: LILRB5
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBYCL-330
Application*: E, WB
Datasheet SDS

Mouse Anti-LILRB5 Recombinant Antibody (CBYJL-1698) (CBMAB-L1577-YJ)

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Target: LILRB5
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBYJL-1698
Application*: WB
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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