LRRC4B

LRRC4B (Leucine Rich Repeat Containing 4B) is a Protein Coding gene. Among its related pathways are Cell adhesion molecules (CAMs). Gene Ontology (GO) annotations related to this gene include signaling receptor binding. An important paralog of this gene is LRRC4C.

Full Name

leucine rich repeat containing 4B

Function

Synaptic adhesion protein. Regulates the formation of excitatory synapses. The trans-synaptic adhesion between LRRC4B and PTPRF regulates the formation of excitatory synapses in a bidirectional manner (By similarity).

Biological Process

Positive regulation of synapse assemblyISS:BHF-UCL
Regulation of postsynaptic density assemblyManual Assertion Based On ExperimentIBA:GO_Central
Regulation of presynapse assemblyManual Assertion Based On ExperimentIBA:GO_Central
Synaptic membrane adhesionManual Assertion Based On ExperimentIBA:GO_Central

Cellular Location

Membrane
Cell junction, synapse, presynaptic cell membrane

Topology

Extracellular: 36-576
Helical: 577-597
Cytoplasmic: 598-713

PTM

N-glycosylated. O-glycosylated; contains sialic acid.

Anti-LRRC4B antibodies

Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

Mouse Anti-LRRC4B Recombinant Antibody (CBWJN-1131) (CBMAB-N0945-WJ)

Datasheet

SDS

Target: LRRC4B

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBWJN-1131

Application*: IH

Mouse Anti-LRRC4B Recombinant Antibody (CBWJN-1130) (CBMAB-N0944-WJ)

Datasheet

SDS

Target: LRRC4B

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human

Clone: CBWJN-1130

Application*: WB

Mouse Anti-LRRC4B Recombinant Antibody (CBYJL-2018) (CBMAB-L2123-YJ)

Datasheet

SDS

Target: LRRC4B

Host: Mouse

Antibody Isotype: IgG2

Specificity: Human

Clone: CBYJL-2018

Application*: WB, E, P

Mouse Anti-LRRC4B Recombinant Antibody (CBYJL-2017) (CBMAB-L2122-YJ)

Datasheet

SDS

Target: LRRC4B

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBYJL-2017

Application*: P

More Infomation

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)