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Mouse Anti-LRRC4B Recombinant Antibody (CBYJL-2018) (CBMAB-L2123-YJ)

Provided herein is a Mouse monoclonal antibody, which binds to Leucine Rich Repeat Containing 4B (LRRC4B). The antibody can be used for immunoassay techniques, such as WB, ELISA, IHC-P.
See all LRRC4B antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBYJL-2018
Antibody Isotype
IgG2
Application
WB, ELISA, IHC-P

Basic Information

Specificity
Human
Antibody Isotype
IgG2
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Buffer
PBS, pH 7.4
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
leucine rich repeat containing 4B
Introduction
Among its related pathways are Cell adhesion molecules (CAMs). Gene Ontology (GO) annotations related to this gene include signaling receptor binding. An important paralog of this gene is LRRC4C.LRRC4B is a synaptic adhesion protein. LRRC4B regulates the formation of excitatory synapses. The trans-synaptic adhesion between LRRC4B and PTPRF regulates the formation of excitatory synapses in a bidirectional manner (By similarity).
Entrez Gene ID
94030
UniProt ID
Q9NT99
Alternative Names
Leucine Rich Repeat Containing 4B; Netrin-G3 Ligand; Leucine-Rich Repeats And Immunoglobulin-Like Domains 4; LRIG4; NGL-3; Leucine-Rich Repeat-Containing Protein 4B; HSM
Function
Synaptic adhesion protein. Regulates the formation of excitatory synapses. The trans-synaptic adhesion between LRRC4B and PTPRF regulates the formation of excitatory synapses in a bidirectional manner (By similarity).
Biological Process
Positive regulation of synapse assemblyISS:BHF-UCL
Regulation of postsynaptic density assemblyManual Assertion Based On ExperimentIBA:GO_Central
Regulation of presynapse assemblyManual Assertion Based On ExperimentIBA:GO_Central
Synaptic membrane adhesionManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Membrane
Cell junction, synapse, presynaptic cell membrane
Topology
Extracellular: 36-576
Helical: 577-597
Cytoplasmic: 598-713
PTM
N-glycosylated. O-glycosylated; contains sialic acid.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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