LRRK1

LRRK1 is a leucine-rich repeat kinase and a GDP/GTP binding protein. LRRK1 is thought to play a role in the regulation of bone mass. Mice lacking a similar gene showed severe osteopetrosis, increased bone mineralization and decreased bone resorption.
Full Name
leucine-rich repeat kinase 1
Biological Process
Bone resorptionIEA:Ensembl
Negative regulation of peptidyl-tyrosine phosphorylationIEA:Ensembl
Osteoclast developmentIEA:Ensembl
Positive regulation of canonical Wnt signaling pathwayManual Assertion Based On ExperimentIGI:ParkinsonsUK-UCL
Positive regulation of intracellular signal transductionIEA:Ensembl
Positive regulation of peptidyl-tyrosine phosphorylationIEA:Ensembl
Signal transductionManual Assertion Based On ExperimentIBA:GO_Central
Cellular Location
Cytoplasm
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Anti-LRRK1 antibodies

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Mouse Anti-LRRK1 Recombinant Antibody (3G8) (CBMAB-A5077-LY)

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Target: LRRK1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: 3G8
Application*: IF, E
Datasheet SDS

Mouse Anti-LRRK1 Recombinant Antibody (CBYCL-489) (CBMAB-L0390-YC)

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Target: LRRK1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBYCL-489
Application*: E, IF, IP
Datasheet SDS

Mouse Anti-LRRK1 Recombinant Antibody (CBYJL-2036) (CBMAB-L2153-YJ)

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Target: LRRK1
Host: Mouse
Antibody Isotype: IgG1, κ
Specificity: Human
Clone: CBYJL-2036
Application*: E, IP
Datasheet SDS

Human Recombinant LRRK1, Active protein, GST Tag (V2LY-0526-LY5370)

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Target: LRRK1
Expressed Host: Baculovirus-Insect Cells
Sequence: Amino Acid: 622-1610
Tag: GST Tag
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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