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LYPLA2

Lysophospholipases are enzymes that act on biological membranes to regulate the multifunctional lysophospholipids. There are alternatively spliced transcript variants described for this gene but the full length nature is not known yet. [provided by RefSeq]
Full Name
lysophospholipase II
Function
Acts as a acyl-protein thioesterase hydrolyzing fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins, GAP43, ZDHHC6 or HRAS (PubMed:21152083, PubMed:28826475).
Deacylates GAP43 (PubMed:21152083).
Mediates depalmitoylation of ZDHHC6 (PubMed:28826475).
Has lysophospholipase activity (PubMed:25301951).
Hydrolyzes prostaglandin glycerol esters (PG-Gs) in the following order prostaglandin D2-glycerol ester (PGD2-G)> prostaglandin E2 glycerol ester (PGE2-G)> prostaglandin F2-alpha-glycerol ester (PGF2-alpha-G) (PubMed:25301951).
Hydrolyzes 1-arachidonoylglycerol but not 2-arachidonoylglycerol or arachidonoylethanolamide (PubMed:25301951).
Biological Process
Acylglycerol catabolic processManual Assertion Based On ExperimentIDA:UniProtKB
Axon guidanceTAS:Reactome
Fatty acid metabolic processIEA:UniProtKB-KW
Prostaglandin catabolic processManual Assertion Based On ExperimentIDA:UniProtKB
Protein depalmitoylationManual Assertion Based On ExperimentIDA:UniProtKB
Cellular Location
Cytoplasm
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Anti-LYPLA2 antibodies

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Mouse Anti-LYPLA2 Recombinant Antibody (CBYCL-598) (CBMAB-L0499-YC)

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Target: LYPLA2
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: CBYCL-598
Application*: E, WB
Datasheet SDS

Mouse Anti-LYPLA2 Recombinant Antibody (CBYJL-2253) (CBMAB-L2513-YJ)

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Target: LYPLA2
Host: Mouse
Antibody Isotype: IgG
Specificity: Human
Clone: CBYJL-2253
Application*: WB, IP, IF, E
Datasheet SDS

Mouse Anti-LYPLA2 Recombinant Antibody (CBYJL-2251) (CBMAB-L2510-YJ)

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Target: LYPLA2
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: CBYJL-2251
Application*: E
Datasheet SDS
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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