MCEE

The product of this gene catalyzes the interconversion of D-and L-methylmalonyl-CoA during the degradation of branched chain amino acids. odd chain-length fatty acids, and other metabolites. Mutations in this gene result in methylmalonyl-CoA epimerase deficiency, which is presented as mild to moderate methylmalonic aciduria.
Full Name
METHYLMALONYL-COA EPIMERASE
Function
Methylmalonyl-CoA epimerase involved in propionyl-CoA metabolism.
Biological Process
L-methylmalonyl-CoA metabolic process Source: UniProtKB
Short-chain fatty acid catabolic process Source: Reactome
Cellular Location
Mitochondrion
Involvement in disease
Methylmalonyl-CoA epimerase deficiency (MCEED):
Autosomal recessive inborn error of amino acid metabolism, involving valine, threonine, isoleucine and methionine. This organic aciduria may present in the neonatal period with life-threatening metabolic acidosis, hyperammonemia, feeding difficulties, pancytopenia and coma.
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Anti-MCEE antibodies

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Mouse Anti-MCEE Recombinant Antibody (CBFYM-1866) (CBMAB-M2037-FY)

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Target: MCEE
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYM-1866
Application*: WB, IH
Datasheet SDS

Mouse Anti-MCEE Recombinant Antibody (6A1) (CBMAB-G6373-LY)

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Target: MCEE
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: 6A1
Application*: P, WB
Datasheet SDS

Mouse Anti-MCEE Recombinant Antibody (1B5) (CBMAB-G6372-LY)

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Target: MCEE
Host: Mouse
Antibody Isotype: IgG2b
Specificity: Human
Clone: 1B5
Application*: P, WB
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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