MCEE

The product of this gene catalyzes the interconversion of D-and L-methylmalonyl-CoA during the degradation of branched chain amino acids. odd chain-length fatty acids, and other metabolites. Mutations in this gene result in methylmalonyl-CoA epimerase deficiency, which is presented as mild to moderate methylmalonic aciduria.

Full Name

METHYLMALONYL-COA EPIMERASE

Function

Methylmalonyl-CoA epimerase involved in propionyl-CoA metabolism.

Biological Process

L-methylmalonyl-CoA metabolic process Source: UniProtKB
Short-chain fatty acid catabolic process Source: Reactome

Cellular Location

Mitochondrion

Involvement in disease

Methylmalonyl-CoA epimerase deficiency (MCEED):
Autosomal recessive inborn error of amino acid metabolism, involving valine, threonine, isoleucine and methionine. This organic aciduria may present in the neonatal period with life-threatening metabolic acidosis, hyperammonemia, feeding difficulties, pancytopenia and coma.

Anti-MCEE antibodies

Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

Mouse Anti-MCEE Recombinant Antibody (CBFYM-1866) (CBMAB-M2037-FY)

Datasheet

SDS

Target: MCEE

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBFYM-1866

Application*: WB, IH

Mouse Anti-MCEE Recombinant Antibody (6A1) (CBMAB-G6373-LY)

Datasheet

SDS

Target: MCEE

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human

Clone: 6A1

Application*: P, WB

Mouse Anti-MCEE Recombinant Antibody (1B5) (CBMAB-G6372-LY)

Datasheet

SDS

Target: MCEE

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: 1B5

Application*: P, WB

More Infomation

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)