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MEF2B

This gene represents numerous read-through transcripts that span geneID:729991 and 100271849. Many read-through transcripts are predicted to be nonsense-mediated decay (NMD) candidates, and are thought to be non-coding. Some transcripts are predicted to be capable of translation reinitation at a downstream AUG, resulting in expression of at least one isoform of myocyte enhancer factor 2B (MEF2B) from this read-through locus. At least one additional MEF2B variant and isoform can be expressed from a downstream promoter, and is annotated on geneID:100271849. [provided by RefSeq]

Full Name

MEF2B

Function

Transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT]4TAR-3', found in numerous muscle-specific genes. Activates transcription via this element. May be involved in muscle-specific and/or growth factor-related transcription.

Biological Process

Cell differentiation Source: GO_Central
Muscle organ development Source: ProtInc
Positive regulation of transcription by RNA polymerase II Source: NTNU_SB
Regulation of transcription by RNA polymerase II Source: GO_Central

Cellular Location

Nucleus

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Anti-MEF2B antibodies

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Mouse Anti-MEF2B Recombinant Antibody (4B5) (CBMAB-A5393-LY)

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Target: MEF2B

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: 4B5

Application*: WB, E

Mouse Anti-MEF2B (AA 1-119) Recombinant Antibody (CBFYM-2027) (CBMAB-M2206-FY)

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Target: MEF2B

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: CBFYM-2027

Application*: E, IF, WB

Mouse Anti-MEF2B (AA 165-235) Recombinant Antibody (CBFYM-2026) (CBMAB-M2205-FY)

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Target: MEF2B

Host: Mouse

Antibody Isotype: IgG2a, κ

Specificity: Human

Clone: CBFYM-2026

Application*: E, WB

Mouse Anti-MEF2B Recombinant Antibody (CBFYM-0619) (CBMAB-M0753-FY)

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Target: MEF2B

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: CBFYM-0619

Application*: E, WB

Mouse Anti-MEF2B Antibody (2F9) (CBMAB-0660-YC)

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Target: MEF2B

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Human

Clone: 2F9

Application*: IP, WB, M

Mouse Anti-MEF2B Antibody (2A11) (CBMAB-0659-YC)

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Target: MEF2B

Host: Mouse

Antibody Isotype: IgG2b

Specificity: Human

Clone: 2A11

Application*: IP, WB, M

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(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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