METAP1D

The N-terminal methionine excision pathway is an essential process in which the N-terminal methionine is removed from many proteins, thus facilitating subsequent protein modification. In mitochondria, enzymes that catalyze this reaction are celled methionine aminopeptidases.
Full Name
METHIONYL AMINOPEPTIDASE TYPE 1D, MITOCHONDRIAL
Function
Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed (By similarity).

May play a role in colon tumorigenesis.
Biological Process
N-terminal protein amino acid modification Source: HGNC-UCL
Peptidyl-methionine modification Source: HGNC-UCL
Protein initiator methionine removal Source: UniProtKB-UniRule
Cellular Location
Mitochondrion
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Anti-METAP1D antibodies

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Rabbit Anti-METAP1D (AA 44-335) Recombinant Antibody (CBFYM-2111) (CBMAB-M2293-FY)

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Target: METAP1D
Host: Rabbit
Antibody Isotype: IgG
Specificity: Human
Clone: CBFYM-2111
Application*: E
Datasheet SDS

Mouse Anti-METAP1D Recombinant Antibody (CBFYM-2110) (CBMAB-M2292-FY)

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Target: METAP1D
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYM-2110
Application*: E, WB
Datasheet SDS

Mouse Anti-METAP1D Recombinant Antibody (CBFYM-2109) (CBMAB-M2291-FY)

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Target: METAP1D
Host: Mouse
Specificity: Human
Clone: CBFYM-2109
Application*: WB, IP, IF, E
Datasheet SDS
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Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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