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METAP1D

The N-terminal methionine excision pathway is an essential process in which the N-terminal methionine is removed from many proteins, thus facilitating subsequent protein modification. In mitochondria, enzymes that catalyze this reaction are celled methionine aminopeptidases.

Full Name

METHIONYL AMINOPEPTIDASE TYPE 1D, MITOCHONDRIAL

Function

Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed (By similarity).

May play a role in colon tumorigenesis.

Biological Process

N-terminal protein amino acid modification Source: HGNC-UCL
Peptidyl-methionine modification Source: HGNC-UCL
Protein initiator methionine removal Source: UniProtKB-UniRule

Cellular Location

Mitochondrion

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Anti-METAP1D antibodies

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Rabbit Anti-METAP1D (AA 44-335) Recombinant Antibody (CBFYM-2111) (CBMAB-M2293-FY)

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Target: METAP1D

Host: Rabbit

Antibody Isotype: IgG

Specificity: Human

Clone: CBFYM-2111

Application*: E

Rabbit Anti-METAP1D (AA 44-335) Recombinant Antibody (CBFYM-2111)

Mouse Anti-METAP1D Recombinant Antibody (CBFYM-2110) (CBMAB-M2292-FY)

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Target: METAP1D

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: CBFYM-2110

Application*: E, WB

Mouse Anti-METAP1D Recombinant Antibody (CBFYM-2110)

Mouse Anti-METAP1D Recombinant Antibody (CBFYM-2109) (CBMAB-M2291-FY)

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Target: METAP1D

Host: Mouse

Specificity: Human

Clone: CBFYM-2109

Application*: WB, IP, IF, E

Mouse Anti-METAP1D Recombinant Antibody (CBFYM-2109)

Human Recombinant MAP1D protein, His Tag (V2LY-0526-LY5426)

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Target: METAP1D

Expressed Host: Baculovirus-Insect Cells

Sequence: Amino Acid: 44-335

Tag: His Tag

Human Recombinant MAP1D protein, His Tag

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized)

Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)

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For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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