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MGST3

The MAPEG (Membrane Associated Proteins in Eicosanoid and Glutathione metabolism) family consists of six human proteins, several of which are involved the production of leukotrienes and prostaglandin E, important mediators of inflammation. This gene encodes an enzyme which catalyzes the conjugation of leukotriene A4 and reduced glutathione to produce leukotriene C4. This enzyme also demonstrates glutathione-dependent peroxidase activity towards lipid hydroperoxides. [provided by RefSeq]

Full Name

microsomal glutathione S-transferase 3

Function

Catalyzes oxydation of hydroxy-fatty acids (PubMed:9278457).

Also catalyzes the conjugation of a reduced glutathione to leukotriene A4 in vitro (PubMed:9278457).

May participate in the lipid metabolism (PubMed:9278457).

Biological Process

Leukotriene biosynthetic process Source: BHF-UCL
Lipid metabolic process Source: BHF-UCL

Cellular Location

Endoplasmic reticulum
Endoplasmic reticulum membrane
Microsome membrane
Other locations
Membrane

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Anti-MGST3 antibodies

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Mouse Anti-MGST3 (AA 1-152) Recombinant Antibody (CBFYM-2194) (CBMAB-M2376-FY)

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Target: MGST3

Host: Mouse

Antibody Isotype: IgG1, κ

Specificity: Human

Clone: CBFYM-2194

Application*: E

Mouse Anti-MGST3 Recombinant Antibody (2G10CG7) (CBMAB-M2377-FY)

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Target: MGST3

Host: Mouse

Antibody Isotype: IgG2a

Specificity: Rat, Human

Clone: 2G10CG7

Application*: IP, IF, E

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(P): Predicted

* Abbreviations

AActivation
AGAgonist
APApoptosis
BBlocking
BABioassay
BIBioimaging
CImmunohistochemistry-Frozen Sections
CIChromatin Immunoprecipitation
CTCytotoxicity
CSCostimulation
DDepletion
DBDot Blot

EELISA
ECELISA(Cap)
EDELISA(Det)
ESELISpot
EMElectron Microscopy
FFlow Cytometry
FNFunction Assay
GSGel Supershift
IInhibition
IAEnzyme Immunoassay
ICImmunocytochemistry
IDImmunodiffusion
IEImmunoelectrophoresis

IFImmunofluorescence
IGImmunochromatography
IHImmunohistochemistry
IMImmunomicroscopy
IOImmunoassay
IPImmunoprecipitation
ISIntracellular Staining for Flow Cytometry
LALuminex Assay
LFLateral Flow Immunoassay
MMicroarray
MCMass Cytometry/CyTOF
MDMeDIP

MSElectrophoretic Mobility Shift Assay
NNeutralization
PImmunohistologyp-Paraffin Sections
PAPeptide Array
PEPeptide ELISA
PLProximity Ligation Assay
RRadioimmunoassay
SStimulation
SESandwich ELISA
SHIn situ hybridization
TCTissue Culture
WBWestern Blot

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