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Mouse Anti-MGST3 Recombinant Antibody (2G10CG7) (CBMAB-M2377-FY)

This product is mouse antibody that recognizes MGST3. The antibody 2G10CG7 can be used for immunoassay techniques such as: IP, IF, ELISA.
See all MGST3 antibodies

Summary

Host Animal
Mouse
Specificity
Rat, Human
Clone
2G10CG7
Antibody Isotype
IgG2a
Application
IP, IF, ELISA

Basic Information

Specificity
Rat, Human
Antibody Isotype
IgG2a
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Concentration
1 mg/mL
Purity
>95% by SDS-PAGE
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
microsomal glutathione S-transferase 3
Introduction
This gene encodes a member of the MAPEG protein family. Members of this family are involved in the production of leukotrienes and prostaglandin E, important mediators of inflammation. This gene encodes an enzyme which catalyzes the conjugation of leukotriene A4 and reduced glutathione to produce leukotriene C4. This enzyme also demonstrates glutathione-dependent peroxidase activity towards lipid hydroperoxides.
Entrez Gene ID
Human4259
Rat289197
UniProt ID
HumanO14880
RatD4ADS4
Alternative Names
Microsomal Glutathione S-Transferase 3; Microsomal GST-III; Microsomal GST-3; Microsomal Glutathione S-Transferase III; EC 2.5.1.18; GST-III
Function
Catalyzes oxydation of hydroxy-fatty acids (PubMed:9278457).

Also catalyzes the conjugation of a reduced glutathione to leukotriene A4 in vitro (PubMed:9278457).

May participate in the lipid metabolism (PubMed:9278457).
Biological Process
Leukotriene biosynthetic process Source: BHF-UCL
Lipid metabolic process Source: BHF-UCL
Cellular Location
Endoplasmic reticulum
Endoplasmic reticulum membrane
Microsome membrane
Other locations
Membrane
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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