MIS12

MIS12 (MIS12, Kinetochore Complex Component) is a protein coding gene. Among its related pathways are Signaling by Rho GTPases and Cell Cycle, Mitotic.

Full Name

MIS12, MIND kinetochore complex component, homolog (yeast)

Function

Part of the MIS12 complex which is required for normal chromosome alignment and segregation and for kinetochore formation during mitosis (PubMed:12515822, PubMed:15502821, PubMed:16585270).

Essential for proper kinetochore microtubule attachments (PubMed:23891108).

Biological Process

Attachment of mitotic spindle microtubules to kinetochore Source: UniProtKB
Cell division Source: UniProtKB-KW
Chromosome segregation Source: UniProtKB
Kinetochore assembly Source: UniProtKB
Mitotic sister chromatid segregation Source: GO_Central
Protein localization to kinetochore Source: GO_Central

Cellular Location

Other locations
kinetochore
Note: Associated with the kinetochore.

Anti-MIS12 antibodies

Mouse Anti-MIS12 Recombinant Antibody (CBFYM-0642) (CBMAB-M0778-FY)

Datasheet

SDS

Target: MIS12

Host: Mouse

Antibody Isotype: IgG2b, κ

Specificity: Human

Clone: CBFYM-0642

Application*: E, WB

Mouse Anti-MIS12 Recombinant Antibody (2572C2a) (CBMAB-M2423-FY)

Datasheet

SDS

Target: MIS12

Host: Mouse

Antibody Isotype: IgG1

Specificity: Human

Clone: 2572C2a

Application*: DB

Recombinant Mouse Anti-MIS12 Recombinant Antibody (QA21-74-4-3) (CBMAB-XB0814-YC)

Datasheet

SDS

Target: MIS12

Host: Mouse

Specificity: Human

Clone: QA21-74-4-3

Application*: WB

For Research Use Only. Not For Clinical Use.

(P): Predicted

* Abbreviations

IFImmunofluorescence

IHImmunohistochemistry

IPImmunoprecipitation

WBWestern Blot

EELISA

MMicroarray

CIChromatin Immunoprecipitation

FFlow Cytometry

FNFunction Assay

IDImmunodiffusion

RRadioimmunoassay

TCTissue Culture

GSGel Supershift

NNeutralization

BBlocking

AActivation

IInhibition

DDepletion

ESELISpot

DBDot Blot

MCMass Cytometry/CyTOF

CTCytotoxicity

SStimulation

AGAgonist

APApoptosis

IMImmunomicroscopy

BABioassay

CSCostimulation

EMElectron Microscopy

IEImmunoelectrophoresis

PAPeptide Array

ICImmunocytochemistry

PEPeptide ELISA

MDMeDIP

SHIn situ hybridization

IAEnzyme Immunoassay

SEsandwich ELISA

PLProximity Ligation Assay

ECELISA(Cap)

EDELISA(Det)

BIBioimaging

IOImmunoassay

LFLateral Flow Immunoassay

LALuminex Assay

CImmunohistochemistry-Frozen Sections

PImmunohistologyp-Paraffin Sections

ISIntracellular Staining for Flow Cytometry

MSElectrophoretic Mobility Shift Assay

RIRNA Binding Protein Immunoprecipitation (RIP)