MIS12

MIS12 (MIS12, Kinetochore Complex Component) is a protein coding gene. Among its related pathways are Signaling by Rho GTPases and Cell Cycle, Mitotic.
Full Name
MIS12, MIND kinetochore complex component, homolog (yeast)
Function
Part of the MIS12 complex which is required for normal chromosome alignment and segregation and for kinetochore formation during mitosis (PubMed:12515822, PubMed:15502821, PubMed:16585270).

Essential for proper kinetochore microtubule attachments (PubMed:23891108).
Biological Process
Attachment of mitotic spindle microtubules to kinetochore Source: UniProtKB
Cell division Source: UniProtKB-KW
Chromosome segregation Source: UniProtKB
Kinetochore assembly Source: UniProtKB
Mitotic sister chromatid segregation Source: GO_Central
Protein localization to kinetochore Source: GO_Central
Cellular Location
Other locations
kinetochore
Note: Associated with the kinetochore.
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Anti-MIS12 antibodies

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Target: MIS12
Host: Mouse
Specificity: Human
Clone: QA21-74-4-3
Application*: WB
Target: MIS12
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: CBFYM-0642
Application*: E, WB
Target: MIS12
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 2572C2a
Application*: DB
More Infomation
Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized) Submit A Review Fig.3 Signaling pathways in cancers. (Creative Biolabs Authorized) Fig.4 Protocols troubleshootings & guides. (Creative Biolabs Authorized)
For Research Use Only. Not For Clinical Use.
(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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