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Mouse Anti-MIS12 Recombinant Antibody (2572C2a) (CBMAB-M2423-FY)

This product is mouse antibody that recognizes MIS12. The antibody 2572C2a can be used for immunoassay techniques such as: Dot.
See all MIS12 antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
2572C2a
Antibody Isotype
IgG1
Application
Dot

Basic Information

Immunogen
Recombinant Human Mis12, Mind Kinetochore Complex Component, Homolog (S.Pombe) (Mis12)
Specificity
Human
Antibody Isotype
IgG1
Clonality
Monoclonal
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, pH 7.4, 1% BSA
Preservative
0.05% Sodium azide
Concentration
0.1 mg/mL
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
MIS12, MIND kinetochore complex component, homolog (yeast)
Introduction
MIS12 is a Protein Coding gene. Among its related pathways are Signaling by Rho GTPases and Cell Cycle, Mitotic.
Entrez Gene ID
79003
UniProt ID
Q9H081
Alternative Names
MIS12, Kinetochore Complex Component; MIS12, MIND Kinetochore Complex Component, Homolog (S. Pombe); MIS12, MIND Kinetochore Complex Component, Homolog (Yeast); MIS12, MIND Kinetochore Complex Component, Homolog; Homolog Of Yeast Mis12; Protein MIS12 Homolog
Function
Part of the MIS12 complex which is required for normal chromosome alignment and segregation and for kinetochore formation during mitosis (PubMed:12515822, PubMed:15502821, PubMed:16585270).

Essential for proper kinetochore microtubule attachments (PubMed:23891108).
Biological Process
Attachment of mitotic spindle microtubules to kinetochore Source: UniProtKB
Cell division Source: UniProtKB-KW
Chromosome segregation Source: UniProtKB
Kinetochore assembly Source: UniProtKB
Mitotic sister chromatid segregation Source: GO_Central
Protein localization to kinetochore Source: GO_Central
Cellular Location
Other locations
kinetochore
Note: Associated with the kinetochore.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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