MTA3

MTA3 (Metastasis Associated 1 Family Member 3) is a Protein Coding gene. Diseases associated with MTA3 include Gastroesophageal Junction Adenocarcinoma. Among its related pathways are Gene Expression and Development NOTCH1-mediated pathway for NF-KB activity modulation. Gene Ontology (GO) annotations related to this gene include DNA binding transcription factor activity and chromatin binding. An important paralog of this gene is MTA1.
Full Name
metastasis associated 1 family, member 3
Function
Plays a role in maintenance of the normal epithelial architecture through the repression of SNAI1 transcription in a histone deacetylase-dependent manner, and thus the regulation of E-cadherin levels. Contributes to transcriptional repression by BCL6.
Biological Process
Chromatin remodeling Source: ComplexPortal
Histone deacetylation Source: ComplexPortal
Negative regulation of transcription, DNA-templated Source: CACAO
Negative regulation of transcription by RNA polymerase II Source: GO_Central
Positive regulation of cell population proliferation Source: Ensembl
Positive regulation of G2/M transition of mitotic cell cycle Source: Ensembl
Positive regulation of transcription, DNA-templated Source: ComplexPortal
Regulation of cell fate specification Source: ComplexPortal
Regulation of stem cell differentiation Source: ComplexPortal
Cellular Location
Nucleus
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Anti-MTA3 antibodies

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Mouse Anti-MTA3 Recombinant Antibody (3C9) (CBMAB-A5653-LY)

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Target: MTA3
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: 3C9
Application*: E, E
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Mouse Anti-MTA3 Recombinant Antibody (2C5) (CBMAB-A5651-LY)

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Target: MTA3
Host: Mouse
Antibody Isotype: IgG2b, κ
Specificity: Human
Clone: 2C5
Application*: IF, E
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Mouse Anti-MTA3 Recombinant Antibody (CBFYM-2716) (CBMAB-M2909-FY)

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Target: MTA3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYM-2716
Application*: WB
Datasheet SDS

Mouse Anti-MTA3 (AA 416-515) Recombinant Antibody (CBFYM-2715) (CBMAB-M2908-FY)

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Target: MTA3
Host: Mouse
Antibody Isotype: IgG2a, κ
Specificity: Human
Clone: CBFYM-2715
Application*: E
Datasheet SDS

Mouse Anti-MTA3 Recombinant Antibody (428C2a) (CBMAB-M2907-FY)

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Target: MTA3
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: 428C2a
Application*: DB
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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