MTRF1L

The protein encoded by this gene plays a role in mitochondrial translation termination, and is thought to be a release factor that is involved in the dissociation of the complete protein from the final tRNA, the ribosome, and the cognate mRNA. This protein acts upon UAA and UAG stop codons, but has no in vitro activity against UGA, which encodes tryptophan in human mitochondrion, or, the mitochondrial non-cognate stop codons, AGA and AGG. This protein shares sequence similarity to bacterial release factors. Pseudogenes of this gene are found on chromosomes 4, 8, and 11. Alternative splicing results in multiple transcript variants.
Full Name
MITOCHONDRIAL TRANSLATIONAL RELEASE FACTOR 1 LIKE
Function
Mitochondrial peptide chain release factor that directs the termination of translation in response to the peptide chain termination codons UAA and UAG.
Biological Process
Mitochondrial translational termination Source: GO_Central
Cellular Location
Mitochondrion
PTM
Methylation of glutamine in the GGQ triplet is conserved from bacteria to mammals.
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Anti-MTRF1L antibodies

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Mouse Anti-MTRF1L Recombinant Antibody (CBFYM-2771) (CBMAB-M2964-FY)

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Target: MTRF1L
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBFYM-2771
Application*: F, IF, IH, P, WB
Datasheet SDS

Mouse Anti-MTRF1L Recombinant Antibody (CBFYH-2661) (CBMAB-H3705-FY)

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Target: MTRF1L
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYH-2661
Application*: IF, P, WB
Datasheet SDS

Mouse Anti-MTRF1L Recombinant Antibody (CBFYH-2660) (CBMAB-H3704-FY)

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Target: MTRF1L
Host: Mouse
Antibody Isotype: IgG1
Specificity: Human
Clone: CBFYH-2660
Application*: F, IF, P, WB
Datasheet SDS

Mouse Anti-MTRF1L Recombinant Antibody (CBFYH-2659) (CBMAB-H3703-FY)

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Target: MTRF1L
Host: Mouse
Antibody Isotype: IgG2a
Specificity: Human
Clone: CBFYH-2659
Application*: F, IF, P, WB
Datasheet SDS
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(P): Predicted
* Abbreviations
  • AActivation
  • AGAgonist
  • APApoptosis
  • BBlocking
  • BABioassay
  • BIBioimaging
  • CImmunohistochemistry-Frozen Sections
  • CIChromatin Immunoprecipitation
  • CTCytotoxicity
  • CSCostimulation
  • DDepletion
  • DBDot Blot
  • EELISA
  • ECELISA(Cap)
  • EDELISA(Det)
  • ESELISpot
  • EMElectron Microscopy
  • FFlow Cytometry
  • FNFunction Assay
  • GSGel Supershift
  • IInhibition
  • IAEnzyme Immunoassay
  • ICImmunocytochemistry
  • IDImmunodiffusion
  • IEImmunoelectrophoresis
  • IFImmunofluorescence
  • IGImmunochromatography
  • IHImmunohistochemistry
  • IMImmunomicroscopy
  • IOImmunoassay
  • IPImmunoprecipitation
  • ISIntracellular Staining for Flow Cytometry
  • LALuminex Assay
  • LFLateral Flow Immunoassay
  • MMicroarray
  • MCMass Cytometry/CyTOF
  • MDMeDIP
  • MSElectrophoretic Mobility Shift Assay
  • NNeutralization
  • PImmunohistologyp-Paraffin Sections
  • PAPeptide Array
  • PEPeptide ELISA
  • PLProximity Ligation Assay
  • RRadioimmunoassay
  • SStimulation
  • SESandwich ELISA
  • SHIn situ hybridization
  • TCTissue Culture
  • WBWestern Blot
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