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Mouse Anti-MTRF1L Recombinant Antibody (CBFYH-2659) (CBMAB-H3703-FY)

This product is mouse antibody that recognizes MTRF1L. The antibody CBFYH-2659 can be used for immunoassay techniques such as: FC, IF, IHC-P, WB.
See all MTRF1L antibodies

Summary

Host Animal
Mouse
Specificity
Human
Clone
CBFYH-2659
Antibody Isotype
IgG2a
Application
FC, IF, IHC-P, WB

Basic Information

Specificity
Human
Antibody Isotype
IgG2a
Application Notes
The COA includes recommended starting dilutions, optimal dilutions should be determined by the end user.

Formulations & Storage [For reference only, actual COA shall prevail!]

Format
Liquid
Buffer
PBS, PH 7.3, 1% BSA, 50% glycerol
Preservative
0.02% Sodium azide
Storage
Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Full Name
MITOCHONDRIAL TRANSLATIONAL RELEASE FACTOR 1 LIKE
Introduction
The protein encoded by this gene plays a role in mitochondrial translation termination, and is thought to be a release factor that is involved in the dissociation of the complete protein from the final tRNA, the ribosome, and the cognate mRNA. This protein acts upon UAA and UAG stop codons, but has no in vitro activity against UGA, which encodes tryptophan in human mitochondrion, or, the mitochondrial non-cognate stop codons, AGA and AGG. This protein shares sequence similarity to bacterial release factors. Pseudogenes of this gene are found on chromosomes 4, 8, and 11. Alternative splicing results in multiple transcript variants.
Entrez Gene ID
54516
UniProt ID
Q9UGC7
Alternative Names
Mitochondrial Translational Release Factor 1 Like; Mitochondrial Translational Release Factor 1-Like; MtRF1a; Peptide Chain Release Factor 1-Like, Mitochondrial; Mitochondrial Release Factor 1 Like; HMRF1L; MRF1L
Function
Mitochondrial peptide chain release factor that directs the termination of translation in response to the peptide chain termination codons UAA and UAG.
Biological Process
Mitochondrial translational termination Source: GO_Central
Cellular Location
Mitochondrion
PTM
Methylation of glutamine in the GGQ triplet is conserved from bacteria to mammals.
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For research use only. Not intended for any clinical use.

Custom Antibody Labeling

We also offer labeled antibodies developed using our catalog antibody products and nonfluorescent conjugates (HRP, AP, Biotin, etc.) or fluorescent conjugates (Alexa Fluor, FITC, TRITC, Rhodamine, Texas Red, R-PE, APC, Qdot Probes, Pacific Dyes, etc.).

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